The very many faces of presenilins and the γ-secretase complex. - Wikidata - wikimedia - TriplyDB

The very many faces of presenilins and the γ-secretase complex.

The very many faces of presenilins and the γ-secretase complex.

http://www.wikidata.org/entity/Q38090514

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Gamma-secretase subunits associate in intracellular membrane compartments in Arabidopsis thaliana.Mitofusin-2 knockdown increases ER-mitochondria contact and decreases amyloid β-peptide production Role of amyloid peptides in vascular dysfunction and platelet dysregulation in Alzheimer's disease Effects of grape seed proanthocyanidin on Alzheimer's disease in vitro and in vivo Autophagic/lysosomal dysfunction in Alzheimer's disease.Presenilin 2 deficiency facilitates Aβ-induced neuroinflammation and injury by upregulating P2X7 expression.Thapsigargin affects presenilin-2 but not presenilin-1 regulation in SK-N-BE cells.Amyloid β-peptide and Alzheimer's disease.Alzheimer's disease-related peptide PS2V plays ancient, conserved roles in suppression of the unfolded protein response under hypoxia and stimulation of γ-secretase activity.Evidence for cadherin-11 cleavage in the synovium and partial characterization of its mechanism.Effects of aluminium on β-amyloid (1-42) and secretases (APP-cleaving enzymes) in rat brain.From the Cover: Comparative Proteomics Reveals Silver Nanoparticles Alter Fatty Acid Metabolism and Amyloid Beta Clearance for Neuronal Apoptosis in a Triple Cell Coculture Model of the Blood-Brain Barrier.Role of Presenilin in Mitochondrial Oxidative Stress and Neurodegeneration in

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The very many faces of presenilins and the γ-secretase complex.

http://www.wikidata.org/entity/Q38090514

description

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artikel ilmiah

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artículo científico

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The very many faces of presenilins and the γ-secretase complex.

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The very many faces of presenilins and the γ-secretase complex.

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The very many faces of presenilins and the γ-secretase complex.

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The very many faces of presenilins and the γ-secretase complex

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Michalina Smolarkiewicz

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Przemysław Wojtaszek

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P2860

A myristoylated calcium-binding protein that preferentially interacts with the Alzheimer's disease presenilin 2 protein

Presenilin 2 interacts with sorcin, a modulator of the ryanodine receptor

Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing

A presenilin-1/gamma-secretase cleavage releases the E-cadherin intracellular domain and regulates disassembly of adherens junctions.

Gamma-secretase activating protein is a therapeutic target for Alzheimer's disease

Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations

Regulation of ApoE receptor proteolysis by ligand binding

Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease

TMP21 is a presenilin complex component that modulates gamma-secretase but not epsilon-secretase activity

CD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide production

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s00709-013-0494-y

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997-1011

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scholarly article

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10.1007/S00709-013-0494-Y

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5

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Tomasz Skrzypczak

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2013-03-16T00:00:00Z

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236056647

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membrane proteins

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3788181

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