Effects of CXCL13 inhibition on lymphoid follicles in models of autoimmune disease. - Wikidata - wikimedia - TriplyDB

Effects of CXCL13 inhibition on lymphoid follicles in models of autoimmune disease.

Effects of CXCL13 inhibition on lymphoid follicles in models of autoimmune disease.

http://www.wikidata.org/entity/Q38091729

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Stromal cell regulation of homeostatic and inflammatory lymphoid organogenesis Roles of the mitochondrial Na(+)-Ca(2+) exchanger, NCLX, in B lymphocyte chemotaxis Serum C-X-C motif chemokine 13 is elevated in early and established rheumatoid arthritis and correlates with rheumatoid factor levels Regulated Production of CXCL13 within the Central Nervous System.The A Allele of the Single-Nucleotide Polymorphism rs630923 Creates a Binding Site for MEF2C Resulting in Reduced CXCR5 Promoter Activity in B-Cell Lymphoblastic Cell Lines.CXCL13 antibody for the treatment of autoimmune disorders.In vitro study of the effect of small interfering ribonucleic acid on the expression of FOXN1 and B cell-attracting chemokine 1 in thymoma cell lines New insights into B cell biology in systemic lupus erythematosus and Sjögren's syndrome Targeting CXCL13 During Neuroinflammation CXCL13 is a plasma biomarker of germinal center activity.CXCL13 promotes isotype-switched B cell accumulation to the central nervous system during viral encephalomyelitis.Novel CXCL13 transgenic mouse: inflammation drives pathogenic effect of CXCL13 in experimental myasthenia gravis.Adaptive human immunity drives remyelination in a mouse model of demyelination Saliva-microbe interactions and salivary gland dysfunction.T cell specific Cxcr5 deficiency prevents rheumatoid arthritis.Successes and failures of chemokine-pathway targeting in rheumatoid arthritis.The role of Bruton's tyrosine kinase in autoimmunity and implications for therapy.Tertiary lymphoid structures, drivers of the anti-tumor responses in human cancers.Tfh cells and HIV bnAbs, an immunodominance model of the HIV neutralizing antibody generation problem.Protective Humoral Immunity in the CNS Requires Peripheral CD19-Dependent Germinal Center Formation Following Coronavirus Encephalomyelitis.T Follicular Helper Cells in Transplantation: The Target to Attenuate Antibody-Mediated Allogeneic Responses?Inflammatory Alteration of Human T Cells Exposed Continuously to Asbestos.Identification of Shared Molecular Signatures Indicate the Susceptibility of Endometriosis to Multiple Sclerosis.Elevated follicular helper T cells and expression of IL-21 in thyroid tissues are involved in the pathogenesis of Graves' disease.Co-expression of CD21L and IL17A defines a subset of rheumatoid synovia, characterised by large lymphoid aggregates and high inflammation

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Effects of CXCL13 inhibition on lymphoid follicles in models of autoimmune disease.

http://www.wikidata.org/entity/Q38091729

description

article científic

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article scientifique

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articol științific

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articolo scientifico

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artikel ilmiah

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Effects of CXCL13 inhibition on lymphoid follicles in models of autoimmune disease.

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type

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Effects of CXCL13 inhibition on lymphoid follicles in models of autoimmune disease.

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prefLabel

Effects of CXCL13 inhibition on lymphoid follicles in models of autoimmune disease.

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European Journal of Clinical Investigation

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Effects of CXCL13 inhibition on lymphoid follicles in models of autoimmune disease.

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Donna K Finch

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Jodi L Karnell

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Matthew A Sleeman

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Rachel Ettinger

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Ronald Herbst

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P2860

Monocyte-like and mature macrophages produce CXCL13 (B cell-attracting chemokine 1) in inflammatory lesions with lymphoid neogenesis

The chemokine CXCL13 is a key molecule in autoimmune myasthenia gravis

B cell-attracting chemokine 1, a human CXC chemokine expressed in lymphoid tissues, selectively attracts B lymphocytes via BLR1/CXCR5

Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production

Chemokine receptors in the rheumatoid synovium: upregulation of CXCR5

Differential expression of chemokine receptors on peripheral blood B cells from patients with rheumatoid arthritis and systemic lupus erythematosus

A chemokine-driven positive feedback loop organizes lymphoid follicles

CXCL13 is required for B1 cell homing, natural antibody production, and body cavity immunity

The role of CXCR5 and its ligand CXCL13 in the compartmentalization of lymphocytes in thyroids affected by autoimmune thyroid diseases

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501-509

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scholarly article

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10.1111/ECI.12063

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5

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43

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2013-03-20T00:00:00Z

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236069372

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23517338

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