When Overgrowth Bumps Into Cancer: The PTEN-Opathies.

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Subcellular targeting and dynamic regulation of PTEN: implications for neuronal cells and neurological disorders Therapeutic targeting of cancers with loss of PTEN function.Mosaic Disorders of the PI3K/PTEN/AKT/TSC/mTORC1 Signaling Pathway.

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When Overgrowth Bumps Into Cancer: The PTEN-Opathies.

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article scientifique

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When Overgrowth Bumps Into Cancer: The PTEN-Opathies.

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When Overgrowth Bumps Into Cancer: The PTEN-Opathies.

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When Overgrowth Bumps Into Cancer: The PTEN-Opathies.

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P1476

When Overgrowth Bumps Into Cancer: The PTEN-Opathies.

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Jessica Mester

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Analysis of prevalence and degree of macrocephaly in patients with germline PTEN mutations and of brain weight in Pten knock-in murine model

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

A mosaic activating mutation in AKT1 associated with the Proteus syndrome

A clinical scoring system for selection of patients for PTEN mutation testing is proposed on the basis of a prospective study of 3042 probands

Germline mutation of the tumour suppressor PTEN in Proteus syndrome

Subset of individuals with autism spectrum disorders and extreme macrocephaly associated with germline PTEN tumour suppressor gene mutations

Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.

Suppression of Peutz-Jeghers polyposis by targeting mammalian target of rapamycin signaling.

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scholarly article

P356

10.1002/J.1552-4876.2013.31364.X

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Charis Eng

P577

2013-04-09T00:00:00Z

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P698

23576530

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When Overgrowth Bumps Into Cancer: The PTEN-Opathies.

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P2860

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When Overgrowth Bumps Into Cancer: The PTEN-Opathies.

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