iPPI-DB: a manually curated and interactive database of small non-peptide inhibitors of protein-protein interactions.
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Small Molecule Targeting of Protein-Protein Interactions through Allosteric Modulation of DynamicsChemical libraries dedicated to protein-protein interactionsRational design of small-molecule stabilizers of spermine synthase dimer by virtual screening and free energy-based approachSmall-molecule inhibitors of protein-protein interactions: progressing toward the reality.Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions.2P2I HUNTER: a tool for filtering orthosteric protein-protein interaction modulators via a dedicated support vector machine.HADDOCK(2P2I): a biophysical model for predicting the binding affinity of protein-protein interaction inhibitors.Focused chemical libraries--design and enrichment: an example of protein-protein interaction chemical space.Identification of Small Inhibitory Molecules Targeting the Bfl-1 Anti-Apoptotic Protein That Alleviates Resistance to ABT-737.Tampering with cell division by using small-molecule inhibitors of CDK-CKS protein interactions.Computational and biophysical approaches to protein-protein interaction inhibition of Plasmodium falciparum AMA1/RON2 complex.MTiOpenScreen: a web server for structure-based virtual screening.FAF-Drugs3: a web server for compound property calculation and chemical library design.Alternative modulation of protein-protein interactions by small moleculesComparative Analysis of Virtual Screening Approaches in the Search for Novel EphA2 Receptor Antagonists.One cannot rule them all: Are bacterial toxins-antitoxins druggable?Imbalance in chemical space: How to facilitate the identification of protein-protein interaction inhibitors.Screening-based approaches to identify small molecules that inhibit protein-protein interactions.iPPI-DB: an online database of modulators of protein-protein interactions.The paramyxovirus polymerase complex as a target for next-generation anti-paramyxovirus therapeutics.Computational analysis of calculated physicochemical and ADMET properties of protein-protein interaction inhibitorsStructure-guided design of small-molecule therapeutics against RSV disease.Computational Biology and Chemistry in MTi: Emphasis on the Prediction of Some ADMET Properties.Computational probing protein-protein interactions targeting small molecules.2P2Idb v2: update of a structural database dedicated to orthosteric modulation of protein-protein interactions.Structure- and ligand-based virtual screening identifies new scaffolds for inhibitors of the oncoprotein MDM2.LMPID: a manually curated database of linear motifs mediating protein-protein interactions.An Intriguing Correlation Based on the Superimposition of Residue Pairs with Inhibitors that Target Protein-Protein Interfaces.Drug-Like Protein-Protein Interaction Modulators: Challenges and Opportunities for Drug Discovery and Chemical Biology.An exploration of the 3D chemical space has highlighted a specific shape profile for the compounds intended to inhibit protein-protein interactions.Functional details of the Mycobacterium tuberculosis VapBC26 toxin-antitoxin system based on a structural study: insights into unique binding and antibiotic peptides.Group-Based Optimization of Potent and Cell-Active Inhibitors of the von Hippel-Lindau (VHL) E3 Ubiquitin Ligase: Structure-Activity Relationships Leading to the Chemical Probe (2S,4R)-1-((S)-2-(1-Cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-Assessment of a Single Decoupling Alchemical Approach for the Calculation of the Absolute Binding Free Energies of Protein-Peptide Complexes.Tranilast directly targets NLRP3 to treat inflammasome-driven diseases.Toward the Discovery of a Novel Class of YAP⁻TEAD Interaction Inhibitors by Virtual Screening Approach Targeting YAP⁻TEAD Protein⁻Protein Interface.Discovery of small molecule inhibitors targeting the SUMO–SIM interaction using a protein interface consensus approachSynthesis of the Src SH2 domain and its application in bioassays for mirror-image screeningEvolution of In Silico Strategies for Protein-Protein Interaction Drug Discovery
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P2860
iPPI-DB: a manually curated and interactive database of small non-peptide inhibitors of protein-protein interactions.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
@gl
artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
iPPI-DB: a manually curated an ...... protein-protein interactions.
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type
label
iPPI-DB: a manually curated an ...... protein-protein interactions.
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iPPI-DB: a manually curated an ...... protein-protein interactions.
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P2093
P1433
P1476
iPPI-DB: a manually curated an ...... protein-protein interactions.
@en
P2093
Bruno O Villoutreix
Céline M Labbé
Guillaume Laconde
Mélaine A Kuenemann
P304
P356
10.1016/J.DRUDIS.2013.05.003
P577
2013-05-17T00:00:00Z