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Novel Natural Product- and Privileged Scaffold-Based Tubulin Inhibitors Targeting the Colchicine Binding SiteIndole Derivatives Isolated from Brown Alga Sargassum thunbergii Inhibit Adipogenesis through AMPK Activation in 3T3-L1 Preadipocytes.Ruthenium-Catalyzed C-H Arylation of Benzoic Acids and Indole Carboxylic Acids with Aryl HalidesA novel indole compound MA-35 attenuates renal fibrosis by inhibiting both TNF-α and TGF-β1 pathwaysRu-catalysed C-H arylation of indoles and pyrroles with boronic acids: scope and mechanistic studiesCrystal structures of four indole derivatives as possible cannabinoid allosteric antagonistsCrystal structures of three indole derivatives: 3-ethnyl-2-methyl-1-phenyl-sulfonyl-1H-indole, 4-phenyl-sulfonyl-3H,4H-cyclo-penta-[b]indol-1(2H)-one and 1-{2-[(E)-2-(5-chloro-2-nitro-phen-yl)ethen-yl]-1-phenyl-sulfonyl-1H-indol-3-yl}ethan-1-one chlA Tryptoline Ring-Distortion Strategy Leads to Complex and Diverse Biologically Active Molecules from the Indole Alkaloid Yohimbine.Diastereoselective Oxidative C-N/C-O and C-N/C-N Bond Formation Tandems Initiated by Visible Light: Synthesis of Fused N-Arylindolines.Sustained Small Molecule Delivery from Injectable Hyaluronic Acid Hydrogels through Host-Guest Mediated RetentionLewis Acid Mediated Vinylogous Additions of Enol Nucleophiles into an α,β-Unsaturated Platinum CarbeneDirect C7 Functionalization of Tryptophan. Synthesis of Methyl (S)-2-((tert-Butoxycarbonyl)amino)-3-(7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indol-3-yl)propanoate.Selective Reduction of Halogenated Nitroarenes with Hydrazine Hydrate in the Presence of Pd/CCrystal structures of four indole derivatives with a phenyl substituent at the 2-position and a carbonyl group at the 3-position: the C(6) N-H⋯O chain remains the same, but the weak reinforcing inter-actions are different.Methyl (2Z)-2-[(2-formyl-3-methyl-1H-indol-1-yl)meth-yl]-3-(4-meth-oxy-phen-yl)prop-2-enoate.Applications of Bartoli indole synthesis.Strategies for the asymmetric functionalization of indoles: an update.Cytotoxicity and Antioxidant Potential of Novel 2-(2-((1H-indol-5yl)methylene)-hydrazinyl)-thiazole Derivatives.Sequential one-pot synthesis of bis(indolyl)glyoxylamides: Evaluation of antibacterial and anticancer activities.Three new indole alkaloid derivatives from the roots of Murraya paniculata.Indole molecules as inhibitors of tubulin polymerization: potential new anticancer agents, an update (2013-2015).Theoretical study of the regioselective cyclization of enaminones in the construction of benzofurans and indoles.Synthesis of Functionalized 1,3,2-Benzodiazaborole Cores Using Bench-Stable Components.Formation and Trapping of Azafulvene Intermediates Derived from Manganese-Mediated Oxidative Malonate Coupling.Allenylphosphine oxides as simple scaffolds for phosphinoylindoles and phosphinoylisocoumarins.C7-derivatization of C3-alkylindoles including tryptophans and tryptamines.N-heterocyclic-carbene-catalyzed synthesis of 2-aryl indoles.Determination of the absolute configuration of compounds bearing chiral quaternary carbon centers using the crystalline sponge method.Divergent Reactivity of Rhodium(I) Carbenes Derived from Indole Annulations.Tryptophan-Containing Non-Cationizable Opioid Peptides - a new chemotype with unusual structure and in vivo activity.α-Diazo oxime ethers for N-heterocycle synthesis.Palladium Catalyzed Asymmetric Three-Component Coupling of Boronic Esters, Indoles, and Allylic Acetates.An efficient synthesis of 4H-pyrano quinolinone derivatives catalysed by a versatile organocatalyst tetra-n-butylammonium fluoride and their pharmacological screening.A concise flow synthesis of indole-3-carboxylic ester and its derivatisation to an auxin mimic.Crystal structures of 1-benzene-sulfon-yl-2-methyl-3-(4-nitro-benzoyl)-2,3-di-hydro-1H-indole and 1-benzene-sulfon-yl-2-methyl-3-[(thio-phen-2-yl)carbon-yl]-2,3-di-hydro-1H-indole.SAR Studies of Indole-5-propanoic Acid Derivatives To Develop Novel GPR40 Agonists.Gold(i)-catalyzed synthesis of 2-substituted indoles from 2-alkynylnitroarenes with diboron as reductant.Bisindole-oxadiazole hybrids, T3P® -mediated synthesis, and appraisal of their apoptotic, antimetastatic, and computational Bcl-2 binding potential.Reversing Polarity: Carbonyl α-Aminations with Nitrogen Nucleophiles.Palladium-catalyzed regioselective C-H fluoroalkylation of indoles at the C4-position.
P2860
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P2860
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Biomedical importance of indoles.
@en
type
label
Biomedical importance of indoles.
@en
prefLabel
Biomedical importance of indoles.
@en
P2093
P2860
P1433
P1476
Biomedical importance of indoles
@en
P2093
Akhilesh Kumar Verma
Chung Hyeok Kim
Eun Ha Choi
Nagendra Kumar Kaushik
Neha Kaushik
P2860
P304
P356
10.3390/MOLECULES18066620
P407
P577
2013-06-06T00:00:00Z