Recent advances in the heterologous expression of microbial natural product biosynthetic pathways.
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Discovery and resupply of pharmacologically active plant-derived natural products: A reviewMarine-derived myxobacteria of the suborder Nannocystineae: An underexplored source of structurally intriguing and biologically active metabolitesLanthipeptides: chemical synthesis versus in vivo biosynthesis as tools for pharmaceutical productionBioprospecting Sponge-Associated Microbes for Antimicrobial CompoundsDirected natural product biosynthesis gene cluster capture and expression in the model bacterium Bacillus subtilisTargeted capture and heterologous expression of the Pseudoalteromonas alterochromide gene cluster in Escherichia coli represents a promising natural product exploratory platform.Fungal artificial chromosomes for mining of the fungal secondary metabolomeNative promoter strategy for high-yielding synthesis and engineering of fungal secondary metabolites.Allopatric integrations selectively change host transcriptomes, leading to varied expression efficiencies of exotic genes in Myxococcus xanthus.Genetic engineering and heterologous expression of the disorazol biosynthetic gene cluster via Red/ET recombineering.Chromosomal position effect influences the heterologous expression of genes and biosynthetic gene clusters in Streptomyces albus J1074.Tailoring pathway modularity in the biosynthesis of erythromycin analogs heterologously engineered in E. coliMultiplexed integrating plasmids for engineering of the erythromycin gene cluster for expression in Streptomyces spp. and combinatorial biosynthesis.Metabolic profiling as a tool for prioritizing antimicrobial compoundsReinvigorating natural product combinatorial biosynthesis with synthetic biologyMapping Microbial Response Metabolomes for Induced Natural Product Discovery.Simple and rapid direct cloning and heterologous expression of natural product biosynthetic gene cluster in Bacillus subtilis via Red/ET recombineering.Alternative hosts for functional (meta)genome analysis.Synthetic biology for the directed evolution of protein biocatalysts: navigating sequence space intelligently.Pseudomonas putida-a versatile host for the production of natural products.Developing Streptomyces venezuelae as a cell factory for the production of small molecules used in drug discovery.Development of an Unnatural Amino Acid Incorporation System in the Actinobacterial Natural Product Producer Streptomyces venezuelae ATCC 15439.Conversion of the high-yield salinomycin producer Streptomyces albus BK3-25 into a surrogate host for polyketide production.Genetic engineering of modular PKSs: from combinatorial biosynthesis to synthetic biology.Engineering microbial hosts for production of bacterial natural productsMetabolic engineering with systems biology tools to optimize production of prokaryotic secondary metabolites.Transformation-associated recombination (TAR) cloning for genomics studies and synthetic biology.Comparative mass spectrometry-based metabolomics strategies for the investigation of microbial secondary metabolites.Engineering the heterologous expression of lanthipeptides in Escherichia coli by multigene assembly.Direct cloning and transplanting of large DNA fragments from Escherichia coli chromosome.High Level of Spinosad Production in the Heterologous Host Saccharopolyspora erythraeaTotal Biosynthesis and Diverse Applications of the Nonribosomal Peptide-Polyketide Siderophore YersiniabactinRational and efficient site-directed mutagenesis of adenylation domain alters relative yields of luminmide derivatives in vivo.Volatiles from nineteen recently genome sequenced actinomycetes.Direct capture and heterologous expression of Salinispora natural product genes for the biosynthesis of enterocin.Inducamides A-C, chlorinated alkaloids from an RNA polymerase mutant strain of Streptomyces sp.Designing overall stoichiometric conversions and intervening metabolic reactions.Generate a bioactive natural product library by mining bacterial cytochrome P450 patterns.PCR-Independent Method of Transformation-Associated Recombination Reveals the Cosmomycin Biosynthetic Gene Cluster in an Ocean Streptomycete.Development of Streptomyces sp. FR-008 as an emerging chassis.
P2860
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P2860
Recent advances in the heterologous expression of microbial natural product biosynthetic pathways.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
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artikull shkencor
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artículo científico
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name
Recent advances in the heterol ...... product biosynthetic pathways.
@en
type
label
Recent advances in the heterol ...... product biosynthetic pathways.
@en
prefLabel
Recent advances in the heterol ...... product biosynthetic pathways.
@en
P2093
P356
P1476
Recent advances in the heterol ...... product biosynthetic pathways.
@en
P2093
Brett A Neilan
Rolf Müller
Sarah E Ongley
Xiaoying Bian
P304
P356
10.1039/C3NP70034H
P577
2013-07-05T00:00:00Z