Successes and failures for drugs in late-stage development for Alzheimer's disease
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Tau Biology and Tau-Directed Therapies for Alzheimer's DiseaseBridging Type 2 Diabetes and Alzheimer's Disease: Assembling the Puzzle Pieces in the Quest for the Molecules With Therapeutic and Preventive PotentialBuilding a pipeline to discover and validate novel therapeutic targets and lead compounds for Alzheimer's disease.Effect of potent γ-secretase modulator in human neurons derived from multiple presenilin 1-induced pluripotent stem cell mutant carriers.Combining two repurposed drugs as a promising approach for Alzheimer's disease therapyInvestigational drugs in Alzheimer's disease: current progress.Eyes-closed task-free electroencephalography in clinical trials for Alzheimer's disease: an emerging method based upon brain dynamics[18F]GE-180 PET Detects Reduced Microglia Activation After LM11A-31 Therapy in a Mouse Model of Alzheimer's Disease.The need for new approaches in CNS drug discovery: Why drugs have failed, and what can be done to improve outcomes.Searching for Multi-Targeting Neurotherapeutics against Alzheimer's: Discovery of Potent AChE-MAO B Inhibitors through the Decoration of the 2H-Chromen-2-one Structural Motif.Pharmacophore modeling, in silico screening, molecular docking and molecular dynamics approaches for potential alpha-delta bungarotoxin-4 inhibitors discovery.Improved Neuroprotection Provided by Drug Combination in Neurons Exposed to Cell-Derived Soluble Amyloid-β Peptide.Prolonged In Vivo Retention of a Cathepsin D Targeted Optical Contrast Agent in a Mouse Model of Alzheimer's Disease.Vitamin D Supplementation Appears to Increase Plasma Aβ40 in Vitamin D Insufficient Older Adults: A Pilot Randomized Controlled Trial.
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Successes and failures for drugs in late-stage development for Alzheimer's disease
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artículo científico
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name
Successes and failures for drugs in late-stage development for Alzheimer's disease
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Successes and failures for drugs in late-stage development for Alzheimer's disease
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prefLabel
Successes and failures for drugs in late-stage development for Alzheimer's disease
@en
P2860
P1433
P1476
Successes and failures for drugs in late-stage development for Alzheimer's disease
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P2093
Camryn Berk
Marwan N Sabbagh
P2860
P2888
P304
P356
10.1007/S40266-013-0108-6
P577
2013-10-01T00:00:00Z