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The TWEAK receptor Fn14 is a potential cell surface portal for targeted delivery of glioblastoma therapeuticsDeletion of TNF-like weak inducer of apoptosis (TWEAK) protects mice from adipose and systemic impacts of severe obesity.FN14 and GRP94 expression are prognostic/predictive biomarkers of brain metastasis outcome that open up new therapeutic strategies.Fn14-Fc suppresses germinal center formation and pathogenic B cells in a lupus mouse model via inhibition of the TWEAK/Fn14 Pathway.Serum Levels of TNF Receptor Ligands Are Dysregulated in Sepsis and Predict Mortality in Critically Ill PatientsTWEAK activation of the non-canonical NF-κB signaling pathway differentially regulates melanoma and prostate cancer cell invasion.Emerging immunotherapies for rheumatoid arthritis.TWEAK-Fn14 Cytokine-Receptor Axis: A New Player of Myocardial Remodeling and Cardiac FailureNeuropsychiatric systemic lupus erythematosus: pathogenesis and biomarkers.Troxis necrosis, a novel mechanism for drug-induced hepatitis secondary to immunomodulatory therapyTargeting STOX1 in the therapy of preeclampsia.A novel llama antibody targeting Fn14 exhibits anti-metastatic activity in vivo.TNF Receptor-Associated Factor 1 is a Major Target of Soluble TWEAK.The Role of Ubiquitination in TWEAK-Stimulated Signaling.TWEAK/Fn14 Axis-Targeted Therapeutics: Moving Basic Science Discoveries to the Clinic.TWEAK/Fn14 Activation Participates in Skin Inflammation.Retinol dehydrogenase-10 promotes development and progression of human glioma via the TWEAK-NF-κB axis.Endogenous TWEAK is critical for regulating the function of mouse uterine natural killer cells in an immunological model of pregnancy loss.Advanced glycation end products attenuate the function of tumor necrosis factor-like weak inducer of apoptosis to regulate the inflammatory response.Soluble TNF-like weak inducer of apoptosis (TWEAK) enhances poly(I:C)-induced RIPK1-mediated necroptosisAutophagy differentially regulates TNF receptor Fn14 by distinct mammalian Atg8 proteins
P2860
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P2860
description
article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
The TWEAK-Fn14 system as a potential drug target.
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type
label
The TWEAK-Fn14 system as a potential drug target.
@en
prefLabel
The TWEAK-Fn14 system as a potential drug target.
@en
P2860
P356
P1476
The TWEAK-Fn14 system as a potential drug target.
@en
P2860
P304
P356
10.1111/BPH.12337
P407
P577
2013-10-01T00:00:00Z