Kinesin spindle protein (KSP) inhibitors in combination with chemotherapeutic agents for cancer therapy.
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KSP inhibitor SB743921 inhibits growth and induces apoptosis of breast cancer cells by regulating p53, Bcl-2, and DTLDownregulation of Kinesin spindle protein inhibits proliferation, induces apoptosis and increases chemosensitivity in hepatocellular carcinoma cells.Chloroquine potentiates the anti-cancer effect of lidamycin on non-small cell lung cancer cells in vitroCentral spindle proteins and mitotic kinesins are direct transcriptional targets of MuvB, B-MYB and FOXM1 in breast cancer cell lines and are potential targets for therapyKinesin spindle protein inhibitor SB743921 induces mitotic arrest and apoptosis and overcomes imatinib resistance of chronic myeloid leukemia cells.Ligand- and structure-based in silico studies to identify kinesin spindle protein (KSP) inhibitors as potential anticancer agents.
P2860
Kinesin spindle protein (KSP) inhibitors in combination with chemotherapeutic agents for cancer therapy.
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Kinesin spindle protein (KSP) ...... tic agents for cancer therapy.
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type
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Kinesin spindle protein (KSP) ...... tic agents for cancer therapy.
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Kinesin spindle protein (KSP) ...... tic agents for cancer therapy.
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P2093
P2860
P356
P1433
P1476
Kinesin spindle protein (KSP) ...... tic agents for cancer therapy.
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P2093
Hualong Song
Rubing Wang
Shanshan Zhou
Shaoshun Li
P2860
P304
P356
10.1002/CMDC.201300228
P577
2013-08-21T00:00:00Z