An overview of the diverse roles of G-protein coupled receptors (GPCRs) in the pathophysiology of various human diseases.
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Synthetic therapeutic gene circuits in mammalian cellsHow genetic errors in GPCRs affect their function: Possible therapeutic strategiesLabel noise in subtype discrimination of class C G protein-coupled receptors: A systematic approach to the analysis of classification errors.Single Molecule Imaging Deciphers the Relation between Mobility and Signaling of a Prototypical G Protein-coupled Receptor in Living Cells.Gs-DREADD Knock-In Mice for Tissue-Specific, Temporal Stimulation of Cyclic AMP SignalingThe effect of alcohol on the differential expression of cluster of differentiation 14 gene, associated pathways, and genetic networkSingle-cell profiling reveals heterogeneity and functional patterning of GPCR expression in the vascular system.G protein-coupled receptors and the regulation of autophagy.The gut microbiome and the brain.The identification of high-affinity G protein-coupled receptor ligands from large combinatorial libraries using multicolor quantum dot-labeled cell-based screening.Quantifying conformational changes in GPCRs: glimpse of a common functional mechanism.Multitarget-directed tricyclic pyridazinones as G protein-coupled receptor ligands and cholinesterase inhibitors.Comparative analyses of downstream signal transduction targets modulated after activation of the AT1 receptor by two β-arrestin-biased agonists.Ammonia Induces Autophagy through Dopamine Receptor D3 and MTORStructural features embedded in G protein-coupled receptor co-crystal structures are key to their success in virtual screening.Molecular biology of gynecological cancer.Directed evolution of G protein-coupled receptors in yeast for higher functional production in eukaryotic expression hosts.G protein-coupled receptor GPR160 is associated with apoptosis and cell cycle arrest of prostate cancer cells.Fluorescent knock-in mice to decipher the physiopathological role of G protein-coupled receptors.Mammalian designer cells: Engineering principles and biomedical applications.Synthetic biology: applying biological circuits beyond novel therapies.Engineering Gene Circuits for Mammalian Cell-Based Applications.Structural complexes of the agonist, inverse agonist and antagonist bound C5a receptor: insights into pharmacology and signaling.RNA interference-mediated silencing of G protein-coupled receptor 137 inhibits human gastric cancer cell growth.Contribution of heteromerization to G protein-coupled receptor function.Structural Stringency of Cholesterol for Membrane Protein Function Utilizing Stereoisomers as Novel Tools: A Review.Corticotropin releasing hormone receptor 2 exacerbates chronic cardiac dysfunction.Designing Safer Analgesics via μ-Opioid Receptor Pathways.Improving virtual screening of G protein-coupled receptors via ligand-directed modeling.Characterizing Dynamic Protein-Protein Interactions Using the Genetically Encoded Split Biosensor Assay Technique Split TEV.Multiplexed profiling of GPCR activities by combining split TEV assays and EXT-based barcoded readouts.The neuropeptide genes SST, TAC1, HCRT, NPY, and GAL are powerful epigenetic biomarkers in head and neck cancer: a site-specific analysis.Systemic and Intra-Habenular Activation of the Orphan G Protein-Coupled Receptor GPR139 Decreases Compulsive-Like Alcohol Drinking and Hyperalgesia in Alcohol-Dependent Rats.Importance of GPCR-Mediated Microglial Activation in Alzheimer's Disease
P2860
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P2860
An overview of the diverse roles of G-protein coupled receptors (GPCRs) in the pathophysiology of various human diseases.
description
article científic
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article scientifique
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articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
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artikull shkencor
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artículo científico
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name
An overview of the diverse rol ...... ogy of various human diseases.
@en
type
label
An overview of the diverse rol ...... ogy of various human diseases.
@en
prefLabel
An overview of the diverse rol ...... ogy of various human diseases.
@en
P1476
An overview of the diverse rol ...... ogy of various human diseases.
@en
P2093
Boon Chin Heng
Dominique Aubel
P304
P356
10.1016/J.BIOTECHADV.2013.08.017
P577
2013-08-30T00:00:00Z