Acquired mutations that affect pre-mRNA splicing in hematologic malignancies and solid tumors.
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Revisiting the case for genetically engineered mouse models in human myelodysplastic syndrome researchAn extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signalSF3B1 mutations constitute a novel therapeutic target in breast cancer.Defective control of pre-messenger RNA splicing in human diseaseThe role of splicing factors in deregulation of alternative splicing during oncogenesis and tumor progressionBiochemical identification of new proteins involved in splicing repression at the Drosophila P-element exonic splicing silencer.Whole-exome sequencing and genome-wide methylation analyses identify novel disease associated mutations and methylation patterns in idiopathic hypereosinophilic syndrome.Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma.Splicing-dependent expression of microRNAs of mirtron origin in human digestive and excretory system cancer cells.Oncogene- and drug resistance-associated alternative exon usage in acute myeloid leukemia (AML).Functional genomics analyses of RNA-binding proteins reveal the splicing regulator SNRPB as an oncogenic candidate in glioblastoma.Molecular pathogenesis of atypical CML, CMML and MDS/MPN-unclassifiable.Splice factor mutations and alternative splicing as drivers of hematopoietic malignancy.Histone H3K4 trimethylation: dynamic interplay with pre-mRNA splicing.The determinants of alternative RNA splicing in human cells.Cryptic splicing events in the iron transporter ABCB7 and other key target genes in SF3B1-mutant myelodysplastic syndromes.Genomic analyses identify molecular subtypes of pancreatic cancer.Graded requirement for the spliceosome in cell cycle progressionInsulin Resistance: Any Role in the Changing Epidemiology of Thyroid Cancer?Modeling Myeloid Malignancies Using Zebrafish.Signaling Pathways Driving Aberrant Splicing in Cancer Cells.Insulin Receptor Isoforms in Physiology and Disease: An Updated View.Molecular Pathways: Understanding and Targeting Mutant Spliceosomal Proteins.SF3B1 mutation is a poor prognostic indicator in luminal B and progesterone receptor-negative breast cancer patients.A common alternative splicing signature is associated with SF3B1 mutations in malignancies from different cell lineages.Disturbed alternative splicing of FIR (PUF60) directed cyclin E overexpression in esophageal cancers.Host-directed combinatorial RNAi improves inhibition of diverse strains of influenza A virus in human respiratory epithelial cells.
P2860
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P2860
Acquired mutations that affect pre-mRNA splicing in hematologic malignancies and solid tumors.
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
@zh-hans
2013年学术文章
@zh-my
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@zh-sg
2013年學術文章
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name
Acquired mutations that affect ...... malignancies and solid tumors.
@en
type
label
Acquired mutations that affect ...... malignancies and solid tumors.
@en
prefLabel
Acquired mutations that affect ...... malignancies and solid tumors.
@en
P2860
P356
P1476
Acquired mutations that affect ...... malignancies and solid tumors.
@en
P2093
Linda M Scott
Vivienne I Rebel
P2860
P304
P356
10.1093/JNCI/DJT257
P407
P577
2013-09-19T00:00:00Z