Chronic inflammation in biomaterial-induced periprosthetic osteolysis: NF-κB as a therapeutic target.
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Metallic debris from metal-on-metal total hip arthroplasty regulates periprosthetic tissuesER Stress Mediates TiAl6V4 Particle-Induced Peri-Implant Osteolysis by Promoting RANKL Expression in FibroblastsMacrophage responses to implants: prospects for personalized medicineThe metal nanoparticle-induced inflammatory response is regulated by SIRT1 through NF-κB deacetylation in aseptic loosening.Interaction of Materials and Biology in Total Joint Replacement - Successes, Challenges and Future Directions.Post-Natal Inhibition of NF-κB Activation Prevents Renal Damage Caused by Prenatal LPS Exposure.Cytokine induction of sol-gel-derived TiO2 and SiO2 coatings on metallic substrates after implantation to rat femurEndoplasmic reticulum stress-mediated inflammatory signaling pathways within the osteolytic periosteum and interface membrane in particle-induced osteolysisInflammation, fracture and bone repair.Autophagy mediated CoCrMo particle-induced peri-implant osteolysis by promoting osteoblast apoptosis.Gelatin-based Hydrogel Degradation and Tissue Interaction in vivo: Insights from Multimodal Preclinical Imaging in Immunocompetent Nude Mice.Blockade of NF-κB and MAPK pathways by ulinastatin attenuates wear particle-stimulated osteoclast differentiation in vitro and in vivo.Aging Affects Bone Marrow Macrophage Polarization: Relevance to Bone Healing.Bay11-7082 attenuates neuropathic pain via inhibition of nuclear factor-kappa B and nucleotide-binding domain-like receptor protein 3 inflammasome activation in dorsal root ganglions in a rat model of lumbar disc herniationNF-κB decoy oligodeoxynucleotide inhibits wear particle-induced inflammation in a murine calvarial model.Suppression of wear-particle-induced pro-inflammatory cytokine and chemokine production in macrophages via NF-κB decoy oligodeoxynucleotide: a preliminary report.RAW 264.7 co-cultured with ultra-high molecular weight polyethylene particles spontaneously differentiate into osteoclasts: an in vitro model of periprosthetic osteolysis.Oxygen plasma surface modification augments poly(L-lactide-co-glycolide) cytocompatibility toward osteoblasts and minimizes immune activation of macrophages.Dendritic cells enhance UHMWPE wear particle-induced osteoclast differentiation of macrophages.Metallic wear debris may regulate CXCR4 expression in vitro and in vivo.Mesenchymal stem cells in the aseptic loosening of total joint replacements.Suppression of NF-κB signaling mitigates polyethylene wear particle-induced inflammatory response.NF-κB as a Therapeutic Target in Inflammatory-Associated Bone Diseases.Gene Expression in Osteolysis: Review on the Identification of Altered Molecular Pathways in Preclinical and Clinical Studies.Decreased osteogenesis in mesenchymal stem cells derived from the aged mouse is associated with enhanced NF-κB activity.Reducing bacteria and macrophage density on nanophase hydroxyapatite coated onto titanium surfaces without releasing pharmaceutical agents.NF-κB decoy oligodeoxynucleotide mitigates wear particle-associated bone loss in the murine continuous infusion model.NF-κB decoy oligodeoxynucleotide enhanced osteogenesis in mesenchymal stem cells exposed to polyethylene particle.Peroxisome proliferator activated receptor gamma loaded dental implant improves osteogenesis of rat mandible.Honokiol ameliorates endothelial dysfunction through suppression of PTX3 expression, a key mediator of IKK/IκB/NF-κB, in atherosclerotic cell model.High glucose alters the secretome of mechanically stimulated osteocyte-like cells affecting osteoclast precursor recruitment and differentiation.Bone regeneration is associated with the concentration of tumour necrosis factor-α induced by sericin released from a silk mat.Orthopaedic wear particle-induced bone loss and exogenous macrophage infiltration is mitigated by local infusion of NF-κB decoy oligodeoxynucleotide.Preconditioning of murine mesenchymal stem cells synergistically enhanced immunomodulation and osteogenesis.Key Triggers of Osteoclast-Related Diseases and Available Strategies for Targeted Therapies: A Review.Review: the potential impact of surface crystalline states of titanium for biomedical applications.CCL2, CCL5, and IGF-1 participate in the immunomodulation of osteogenesis during M1/M2 transition in vitro.Mammalian target of rapamycin as a therapeutic target in osteoporosis.Dicalcium Silicate Induced Proinflammatory Responses through TLR2-Mediated NF-κB and JNK Pathways in the Murine RAW 264.7 Macrophage Cell Line.Paeoniflorin regulates osteoclastogenesis and osteoblastogenesis via manipulating NF-κB signaling pathway both in vitro and in vivo.
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Chronic inflammation in biomaterial-induced periprosthetic osteolysis: NF-κB as a therapeutic target.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
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name
Chronic inflammation in biomat ...... NF-κB as a therapeutic target.
@en
type
label
Chronic inflammation in biomat ...... NF-κB as a therapeutic target.
@en
prefLabel
Chronic inflammation in biomat ...... NF-κB as a therapeutic target.
@en
P2093
P2860
P1433
P1476
Chronic inflammation in biomat ...... NF-κB as a therapeutic target
@en
P2093
Deanna K Woo
Heather A Waters
Jukka Pajarinen
Stuart B Goodman
Yasunobu Tamaki
Zhenyu Yao
P2860
P356
10.1016/J.ACTBIO.2013.09.034
P50
P577
2013-10-01T00:00:00Z