Heterologous expression of natural product biosynthetic gene clusters in Streptomyces coelicolor: from genome mining to manipulation of biosynthetic pathways.
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Next Generation Sequencing of Actinobacteria for the Discovery of Novel Natural ProductsLessons learned from the transformation of natural product discovery to a genome-driven endeavorMicrobial genome mining for accelerated natural products discovery: is a renaissance in the making?Emerging strategies and integrated systems microbiology technologies for biodiscovery of marine bioactive compounds.The Streptomyces leeuwenhoekii genome: de novo sequencing and assembly in single contigs of the chromosome, circular plasmid pSLE1 and linear plasmid pSLE2Precise cloning and tandem integration of large polyketide biosynthetic gene cluster using Streptomyces artificial chromosome system.Activation of Antibiotic Production in Bacillus spp. by Cumulative Drug Resistance Mutations.Activity-Independent Discovery of Secondary Metabolites Using Chemical Elicitation and Cheminformatic InferenceOne-pot synthesis of class II lanthipeptide bovicin HJ50 via an engineered lanthipeptide synthetase.Actinomycetes biosynthetic potential: how to bridge in silico and in vivo?Discovering new bioactive molecules from microbial sources.The re-emerging role of microbial natural products in antibiotic discovery.Toward a new focus in antibiotic and drug discovery from the Streptomyces arsenalGenetic manipulation of secondary metabolite biosynthesis for improved production in Streptomyces and other actinomycetes.Development of an Unnatural Amino Acid Incorporation System in the Actinobacterial Natural Product Producer Streptomyces venezuelae ATCC 15439.Engineering microbial hosts for production of bacterial natural productsComparative mass spectrometry-based metabolomics strategies for the investigation of microbial secondary metabolites.Challenges in the Heterologous Production of Antibiotics in Streptomyces.Insights into microbial cryptic gene activation and strain improvement: principle, application and technical aspects.Molecular beacons to identify gifted microbes for genome mining.Endophytic actinobacteria: Diversity, secondary metabolism and mechanisms to unsilence biosynthetic gene clusters.Lincomycin at Subinhibitory Concentrations Potentiates Secondary Metabolite Production by Streptomyces spp.DNA affinity capturing identifies new regulators of the heterologously expressed novobiocin gene cluster in Streptomyces coelicolor M512.Complete Genome Sequence of Streptomyces venezuelae ATCC 15439, Producer of the Methymycin/Pikromycin Family of Macrolide Antibiotics, Using PacBio Technology.Evidence for an iterative module in chain elongation on the azalomycin polyketide synthase.Wide Distribution of Foxicin Biosynthetic Gene Clusters in Streptomyces Strains - An Unusual Secondary Metabolite with Various Properties.Recently published Streptomyces genome sequences.Inducamides A-C, chlorinated alkaloids from an RNA polymerase mutant strain of Streptomyces sp.Biosynthetic Pathway Connects Cryptic Ribosomally Synthesized Posttranslationally Modified Peptide Genes with Pyrroloquinoline Alkaloids.Actinomycetes: still a source of novel antibiotics.Derivatives of Holomycin and Cyclopropaneacetic Acid from Streptomyces sp. DT-A37.Bioprospecting of Novel and Bioactive Compounds from Marine Actinomycetes Isolated from South China Sea Sediments.The Immunosuppressant Brasilicardin: Determination of the Biosynthetic Gene Cluster in the Heterologous Host Amycolatopsis japonicum.Establishing a high yielding streptomyces-based cell-free protein synthesis system.MbtH homology codes to identify gifted microbes for genome mining.Selection of an efficient promoter and its application in toyocamycin production improvement in Streptomyces diastatochromogenes 1628.High production of a class III lantipeptide AmfS in Streptomyces griseus.Biomass-derived molecules modulate the behavior of Streptomyces coelicolor for antibiotic production.The Draft Genome Sequence of Actinokineospora bangkokensis 44EHWT Reveals the Biosynthetic Pathway of the Antifungal Thailandin Compounds with Unusual Butylmalonyl-CoA Extender Units.Rapid determination of the amino acid configuration of xenotetrapeptide.
P2860
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P2860
Heterologous expression of natural product biosynthetic gene clusters in Streptomyces coelicolor: from genome mining to manipulation of biosynthetic pathways.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
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name
Heterologous expression of nat ...... tion of biosynthetic pathways.
@en
type
label
Heterologous expression of nat ...... tion of biosynthetic pathways.
@en
prefLabel
Heterologous expression of nat ...... tion of biosynthetic pathways.
@en
P2860
P1476
Heterologous expression of nat ...... tion of biosynthetic pathways.
@en
P2093
Mervyn J Bibb
P2860
P304
P356
10.1007/S10295-013-1348-5
P577
2013-10-06T00:00:00Z