Effects of 5-azacytidine and its 2'-deoxyderivative on cell differentiation and DNA methylation.
about
The quest for an effective and safe personalized cell therapy using epigenetic tools5-azacytidine and 5-azadeoxycytidine inhibit human immunodeficiency virus type 1 replication in vitroThe cancer-associated CTCFL/BORIS protein targets multiple classes of genomic repeats, with a distinct binding and functional preference for humanoid-specific SVA transposable elementsDemethylating Agents in the Treatment of CancerIdentification of novel DNA methylation inhibitors via a two-component reporter gene system.Application of epigenome-modifying small molecules in induced pluripotent stem cells.Methylation and colorectal cancer.Genetic analysis of the 5-azacytidine sensitivity of Escherichia coli K-12.Acetylation-induced transcription is required for active DNA demethylation in methylation-silenced genes.Activation of an imprinted Igf 2 gene in mouse somatic cell cultures.Transcription signatures encoded by ultraconserved genomic regions in human prostate cancer.Efficacy and safety of extended dosing schedules of CC-486 (oral azacitidine) in patients with lower-risk myelodysplastic syndromes.DNA methylation in breast and colorectal cancers.Brief demethylation step allows the conversion of adult human skin fibroblasts into insulin-secreting cells5-azacytidine affects TET2 and histone transcription and reshapes morphology of human skin fibroblasts.Heterogeneity in the mycelium: implications for the use of fungi as cell factories.Prospects for the development of epigenetic drugs for CNS conditions.Erase and Rewind: Epigenetic Conversion of Cell Fate.The radiosensitizing effect of fluorocyclopentenyl-cytosine (RX-3117) in ovarian and lung cancer cell lines.DNA methyltransferase 1 knockdown activates a replication stress checkpoint.Promoter methylation and tissue-specific transcription of the α7 nicotinic receptor gene, CHRNA7.Dysdifferentiation hypothesis of aging and cancer: a comparison with the membrane hypothesis of aging.5-aza-2'-deoxycytidine (DAC) treatment downregulates the HPV E6 and E7 oncogene expression and blocks neoplastic growth of HPV-associated cancer cells.Epigenomic stress response. Knockdown of DNA methyltransferase 1 triggers an intra-S-phase arrest of DNA replication and induction of stress response genes.In vitro assessment of cytochrome P450 inhibition and induction potential of azacitidine.Cell cycle-dependent transcription of cyclin B2 is influenced by DNA methylation but is independent of methylation in the CDE and CHR elements.Expression of markers for germ cells and oocytes in cow dermal fibroblast treated with 5-azacytidine and cultured in differentiation medium containing BMP2, BMP4 or follicular fluid.Hypomethylation of ras oncogenes in chemically induced and spontaneous B6C3F1 mouse liver tumors.
P2860
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P2860
Effects of 5-azacytidine and its 2'-deoxyderivative on cell differentiation and DNA methylation.
description
article científic
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article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Effects of 5-azacytidine and i ...... entiation and DNA methylation.
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type
label
Effects of 5-azacytidine and i ...... entiation and DNA methylation.
@en
prefLabel
Effects of 5-azacytidine and i ...... entiation and DNA methylation.
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P1476
Effects of 5-azacytidine and i ...... entiation and DNA methylation.
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P2093
P356
10.1016/0163-7258(85)90080-4
P577
1985-01-01T00:00:00Z