Pharmacological properties of shikonin - a review of literature since 2002.
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Shikonin Inhibits Inflammatory Response in Rheumatoid Arthritis Synovial Fibroblasts via lncRNA-NR024118.Biosynthesis and molecular actions of specialized 1,4-naphthoquinone natural products produced by horticultural plantsThe Combination of Three Natural Compounds Effectively Prevented Lung Carcinogenesis by Optimal Wound HealingAcetylshikonin from Zicao Prevents Obesity in Rats on a High-Fat Diet by Inhibiting Lipid Accumulation and Inducing LipolysisAnti-tumor effects of shikonin derivatives on human medullary thyroid carcinoma cells.In vitro induction of erythrocyte phosphatidylserine translocation by the natural naphthoquinone shikonin.Identification of New Shikonin Derivatives as Antitumor Agents Targeting STAT3 SH2 Domain.PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis.The inhibitory effect of shikonin on the agonist-induced regulation of vascular contractility.Inhibition of STAT3, FAK and Src mediated signaling reduces cancer stem cell load, tumorigenic potential and metastasis in breast cancer.Shikonin Suppresses NLRP3 and AIM2 Inflammasomes by Direct Inhibition of Caspase-1.β-hydroxyisovaleryl-shikonin induces human cervical cancer cell apoptosis via PI3K/AKT/mTOR signalingInhibition of c-MYC with involvement of ERK/JNK/MAPK and AKT pathways as a novel mechanism for shikonin and its derivatives in killing leukemia cells.Exploratory, Phase II Controlled Trial of Shiunko Ointment Local Application Twice a Day for 4 Weeks in Ethiopian Patients with Localized Cutaneous Leishmaniasis.Shikonin Inhibits Intestinal Calcium-Activated Chloride Channels and Prevents Rotaviral Diarrhea.Quantitative Non-canonical Amino Acid Tagging (QuaNCAT) Proteomics Identifies Distinct Patterns of Protein Synthesis Rapidly Induced by Hypertrophic Agents in Cardiomyocytes, Revealing New Aspects of Metabolic Remodeling.Homocysteine Activates B Cells via Regulating PKM2-Dependent Metabolic Reprogramming.Immunogenicity of mammary tumor cells can be induced by shikonin via direct binding-interference with hnRNPA1.Biotechnological approaches to the production of shikonins: a critical review with recent updates.Shikonin changes the lipopolysaccharide-induced expression of inflammation-related genes in macrophages.Metabolic profiling study of shikonin's cytotoxic activity in the Huh7 human hepatoma cell line.Design, Synthesis, and Biological Evaluation of Chalcone-Containing Shikonin Derivatives as Inhibitors of Tubulin Polymerization.Shikonin Inhibits the Proliferation of Human Breast Cancer Cells by Reducing Tumor-Derived Exosomes.Shikonin Inhibits the Migration and Invasion of Human Glioblastoma Cells by Targeting Phosphorylated β-Catenin and Phosphorylated PI3K/Akt: A Potential Mechanism for the Anti-Glioma Efficacy of a Traditional Chinese Herbal MedicineShikonin inhibits invasiveness of osteosarcoma through MMP13 suppression.Antiviral activity of shikonin ester derivative PMM-034 against enterovirus 71 in vitro.Inhibition of neutrophil superoxide generation by shikonin is associated with suppression of cellular Ca(2+) fluxes.Antibacterial and cytotoxic activities of naphthoquinone pigments from Onosma visianii Clem.Wound Healing Effect of Arnebia euchroma gel on Excisional Wounds in Rats.Shikonin promotes adriamycin‑induced apoptosis by upregulating caspase‑3 and caspase‑8 in osteosarcoma.Efficacy of Shikonin against Esophageal Cancer Cells and its possible mechanisms in vitro and in vivo.Involvement of LeMDR, an ATP-binding cassette protein gene, in shikonin transport and biosynthesis in Lithospermum erythrorhizon.Shikonin inhibits myeloid differentiation protein-2 to prevent lipopolysaccharide-induced acute lung injury.Involvement of LeMRP, an ATP-binding cassette transporter, in shikonin transport and biosynthesis in Lithospermum erythrorhizon.Development of a novel hollow-fiber liquid-phase microextraction based on oil-in-salt and its comparison with conventional one.RNA-seq transcriptome analysis of breast cancer cell lines under shikonin treatment.Production of 3-geranyl-4-hydroxybenzoate acid in yeast, an important intermediate of shikonin biosynthesis pathway.Efficacy of Acetylshikonin in Preventing Obesity and Hepatic Steatosis in db/db Mice.Antinociceptive properties of shikonin: in vitro and in vivo studies.Sarcoma-Targeting Peptide-Decorated Polypeptide Nanogel Intracellularly Delivers Shikonin for Upregulated Osteosarcoma Necroptosis and Diminished Pulmonary Metastasis.
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P2860
Pharmacological properties of shikonin - a review of literature since 2002.
description
article científic
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article scientifique
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articol științific
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articolo scientifico
@it
artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artikull shkencor
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artículo científico
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name
Pharmacological properties of shikonin - a review of literature since 2002.
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type
label
Pharmacological properties of shikonin - a review of literature since 2002.
@en
prefLabel
Pharmacological properties of shikonin - a review of literature since 2002.
@en
P356
P1433
P1476
Pharmacological properties of shikonin - a review of literature since 2002
@en
P2093
José Luis Ríos
María Carmen Recio
P304
P356
10.1055/S-0033-1350934
P577
2013-10-23T00:00:00Z