Allogeneic stem cell transplantation and targeted therapy for FLT3/ITD+ acute myeloid leukemia: an update. - Wikidata - wikimedia - TriplyDB

Allogeneic stem cell transplantation and targeted therapy for FLT3/ITD+ acute myeloid leukemia: an update.

Allogeneic stem cell transplantation and targeted therapy for FLT3/ITD+ acute myeloid leukemia: an update.

http://www.wikidata.org/entity/Q38168893

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Investigational FMS-like tyrosine kinase 3 inhibitors in treatment of acute myeloid leukemia Single-agent GVHD prophylaxis with posttransplantation cyclophosphamide after myeloablative, HLA-matched BMT for AML, ALL, and MDS.Optimal therapy for adult patients with acute myeloid leukemia in first complete remission.Inching toward cure of acute myeloid leukemia: a summary of the progress made in the last 50 years.Relapse of AML after hematopoietic stem cell transplantation: methods of monitoring and preventive strategies. A review from the ALWP of the EBMT.The Challenge of t (6;9) and FLT3-Positive Acute Myelogenous Leukemia in a Young Adult.Use of sorafenib for post-transplant relapse in FLT3/ITD-positive acute myelogenous leukemia: maturation induction and cytotoxic effect.Timed sequential therapy for acute myelogenous leukemia: Results of a retrospective study of 301 patients and review of the literature.Mild chronic graft-versus-host disease may alleviate poor prognosis associated with FLT3 internal tandem duplication for adult acute myeloid leukemia following allogeneic stem cell transplantation with myeloablative conditioning in first complete re

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Allogeneic stem cell transplantation and targeted therapy for FLT3/ITD+ acute myeloid leukemia: an update.

http://www.wikidata.org/entity/Q38168893

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Allogeneic stem cell transplan ...... e myeloid leukemia: an update.

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Allogeneic stem cell transplan ...... e myeloid leukemia: an update.

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Allogeneic stem cell transplan ...... e myeloid leukemia: an update.

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17474086.2014.857596

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Expert Review of Hematology

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Allogeneic stem cell transplan ...... te myeloid leukemia: an update

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Bipin N Savani

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Mohamad Mohty

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The role of FLT3 in haematopoietic malignancies

Activating mutation of D835 within the activation loop of FLT3 in human hematologic malignancies.

Single-agent CEP-701, a novel FLT3 inhibitor, shows biologic and clinical activity in patients with relapsed or refractory acute myeloid leukemia.

FLT3-ITD-TKD dual mutants associated with AML confer resistance to FLT3 PTK inhibitors and cytotoxic agents by overexpression of Bcl-x(L).

Prognostic relevance of FLT3-TKD mutations in AML: the combination matters--an analysis of 3082 patients.

Mutant FLT3: a direct target of sorafenib in acute myelogenous leukemia.

Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia.

Phase IIB trial of oral Midostaurin (PKC412), the FMS-like tyrosine kinase 3 receptor (FLT3) and multi-targeted kinase inhibitor, in patients with acute myeloid leukemia and high-risk myelodysplastic syndrome with either wild-type or mutated FLT3.

Sorafenib treatment of FLT3-ITD(+) acute myeloid leukemia: favorable initial outcome and mechanisms of subsequent nonresponsiveness associated with the emergence of a D835 mutation.

Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia.

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