Ribosome-targeting antibiotics and mechanisms of bacterial resistance.
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Techniques for Screening Translation InhibitorsMechanisms of Antimicrobial Resistance in ESKAPE PathogensPersisters-as elusive as evertRNAs as antibiotic targetsStructure based approaches for targeting non-coding RNAs with small moleculesMolecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA.Synergy of Streptogramin Antibiotics Occurs Independently of Their Effects on TranslationThe proline-rich antimicrobial peptide Onc112 inhibits translation by blocking and destabilizing the initiation complexTargeting Antibiotic ResistanceGenome-Wide Identification of Antimicrobial Intrinsic Resistance Determinants in Staphylococcus aureusSynthesis and evaluation of chloramphenicol homodimers: molecular target, antimicrobial activity, and toxicity against human cellsTargeting an Essential GTPase Obg for the Development of Broad-Spectrum AntibioticsComputational Discovery of Putative Leads for Drug Repositioning through Drug-Target Interaction PredictionBiochemical and structural characterization of polyphosphate kinase 2 from the intracellular pathogen Francisella tularensisResistance-resistant antibioticsThe Identification of Intrinsic Chloramphenicol and Tetracycline Resistance Genes in Members of the Bacillus cereus Group (sensu lato)PA3297 Counteracts Antimicrobial Effects of Azithromycin in Pseudomonas aeruginosa.Assembly and clustering of natural antibiotics guides target identificationAntibiotics: where to throw the spanner in the ribosomal machinery?Tedizolid Phosphate: a Next-Generation Oxazolidinone.The impact of recent improvements in cryo-electron microscopy technology on the understanding of bacterial ribosome assembly.The Importance of Bacterial Culture to Food Microbiology in the Age of GenomicsStructural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome.Lomofungin and dilomofungin: inhibitors of MBNL1-CUG RNA binding with distinct cellular effects.Madumycin II inhibits peptide bond formation by forcing the peptidyl transferase center into an inactive state.Expansion of the aminoglycoside-resistance 16S rRNA (m(1)A1408) methyltransferase family: expression and functional characterization of four hypothetical enzymes of diverse bacterial origin.Arabidopsis small nucleolar RNA monitors the efficient pre-rRNA processing during ribosome biogenesis.Binding induced RNA conformational changes control substrate recognition and catalysis by the thiostrepton resistance methyltransferase (Tsr).The bacterial translation stress response.Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosomeBactobolin A binds to a site on the 70S ribosome distinct from previously seen antibioticsFluorescence-based monitoring of ribosome assembly landscapes.Nonsense suppression by near-cognate tRNAs employs alternative base pairing at codon positions 1 and 3.Regulatory RNAs involved in bacterial antibiotic resistance.Fusidic acid targets elongation factor G in several stages of translocation on the bacterial ribosome.Cryo-EM structure of the tetracycline resistance protein TetM in complex with a translating ribosome at 3.9-Å resolution.Microscale Adaptation of In Vitro Transcription/Translation for High-Throughput Screening of Natural Product Extract Libraries.Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201ASkin Commensal Staphylococci May Act as Reservoir for Fusidic Acid Resistance GenesAntibiotic efficacy is linked to bacterial cellular respiration.
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Ribosome-targeting antibiotics and mechanisms of bacterial resistance.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Ribosome-targeting antibiotics and mechanisms of bacterial resistance.
@en
type
label
Ribosome-targeting antibiotics and mechanisms of bacterial resistance.
@en
prefLabel
Ribosome-targeting antibiotics and mechanisms of bacterial resistance.
@en
P356
P1476
Ribosome-targeting antibiotics and mechanisms of bacterial resistance
@en
P2093
Daniel N Wilson
P2888
P356
10.1038/NRMICRO3155
P407
P577
2014-01-01T00:00:00Z
P5875
P6179
1029239937