Protein kinase C and cancer: what we know and what we do not.
about
Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatasesReduction-oxidation pathways involved in cancer development: a systematic review of literature reviews.Protein Kinases C-Mediated Regulations of Drug Transporter Activity, Localization and Expression.Protein kinase C inhibitor chelerythrine selectively inhibits proliferation of triple-negative breast cancer cells.Novel small molecule inhibiting CDCP1-PKCδ pathway reduces tumor metastasis and proliferation.The novel phospholipid mimetic KPC34 is highly active against preclinical models of Philadelphia chromosome positive acute lymphoblastic leukemia.Transcriptional regulation of oncogenic protein kinase Cϵ (PKCϵ) by STAT1 and Sp1 proteins.Protein kinase Cα mediates erlotinib resistance in lung cancer cells.5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA): showing a strategy of designing drug to block lung metastasis of tumors.Rational design and validation of an anti-protein kinase C active-state specific antibody based on conformational changesSuppression of the invasive potential of Glioblastoma cells by mTOR inhibitors involves modulation of NFκB and PKC-α signaling.Immunohistochemical Markers Distinguishing Cholangiocellular Carcinoma (CCC) from Pancreatic Ductal Adenocarcinoma (PDAC) Discovered by Proteomic Analysis of Microdissected CellsPKCδ regulates integrin αVβ3 expression and transformed growth of K-ras dependent lung cancer cells.miR-150 exerts antileukemia activity in vitro and in vivo through regulating genes in multiple pathwaysLanatoside C, a cardiac glycoside, acts through protein kinase Cδ to cause apoptosis of human hepatocellular carcinoma cells.Acyl-CoA thioesterase 7 is involved in cell cycle progression via regulation of PKCζ-p53-p21 signaling pathway.Biliverdin reductase: a target for cancer therapy?An overview of tyrosine kinase inhibitors for the treatment of epithelial ovarian cancer.A data mining approach for identifying pathway-gene biomarkers for predicting clinical outcome: A case study of erlotinib and sorafenib.Protein Kinase C Epsilon Cooperates with PTEN Loss for Prostate Tumorigenesis through the CXCL13-CXCR5 Pathway.Interacting post-muscarinic receptor signaling pathways potentiate matrix metalloproteinase-1 expression and invasion of human colon cancer cells.Herbal Medicine Offered as an Initiative Therapeutic Option for the Management of Hepatocellular Carcinoma.Protein Kinase C Isoforms Differentially Regulate Hypoxia-Inducible Factor-1α Accumulation in Cancer Cells.Protein kinase C in cancer: The top five unanswered questions.Reversing the Paradigm: Protein Kinase C as a Tumor Suppressor.Protein kinase C as a tumor suppressor.Signaling coupled epigenomic regulation of gene expression.Tetrandrine, an Activator of Autophagy, Induces Autophagic Cell Death via PKC-α Inhibition and mTOR-Dependent Mechanisms.Identification of miR-34a-target interactions by a combined network based and experimental approach.The tumor promoter-activated protein kinase Cs are a system for regulating filopodia.Ral A, via activating the mitotic checkpoint, sensitizes cells lacking a functional Nf1 to apoptosis in the absence of protein kinase C.Interfacial partitioning of a loop hinge residue contributes to diacylglycerol affinity of conserved region 1 domains.Molecular mechanism underlying the pharmacological interactions of the protein kinase C-β inhibitor enzastaurin and erlotinib in non-small cell lung cancer cellsNestin expression is upregulated in the fibrotic rat heart and is localized in collagen-expressing mesenchymal cells and interstitial CD31(+)- cells.Co-dependency of PKCδ and K-Ras: inverse association with cytotoxic drug sensitivity in KRAS mutant lung cancer.OSU-2S/Sorafenib Synergistic Antitumor Combination against Hepatocellular Carcinoma: The Role of PKCδ/p53.Identification and characterisation of lamprey protein kinase C delta-like gene.Downregulation of PKCζ/Pard3/Pard6b is responsible for lung adenocarcinoma cell EMT and invasion.Exploration of charge states of balanol analogues acting as ATP-competitive inhibitors in kinases.Sphingosine 1-phosphate (S1P) signaling in glioblastoma multiforme-A systematic review.
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Protein kinase C and cancer: what we know and what we do not.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
Protein kinase C and cancer: what we know and what we do not.
@en
type
label
Protein kinase C and cancer: what we know and what we do not.
@en
prefLabel
Protein kinase C and cancer: what we know and what we do not.
@en
P2093
P2860
P356
P1433
P1476
Protein kinase C and cancer: what we know and what we do not.
@en
P2093
L G Benedetti
M G Kazanietz
P2860
P2888
P304
P356
10.1038/ONC.2013.524
P407
P577
2013-12-16T00:00:00Z
P6179
1000098148