Alternative splicing in cancer: implications for biology and therapy.
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Expression of evolutionarily novel genes in tumorsNovel Molecular Markers for Breast CancerAberrant Splicing of Estrogen Receptor, HER2, and CD44 Genes in Breast CancerNext-Generation Sequencing Approaches in Cancer: Where Have They Brought Us and Where Will They Take Us?Wrecked regulation of intrinsically disordered proteins in diseases: pathogenicity of deregulated regulatorsDifferential Impacts of Alternative Splicing Networks on ApoptosisDysregulation of ubiquitin ligases in cancerTowards improved genome-scale metabolic network reconstructions: unification, transcript specificity and beyondDiscovery of new candidate genes for rheumatoid arthritis through integration of genetic association data with expression pathway analysis.Pathobiological implications of the d16HER2 splice variant for stemness and aggressiveness of HER2-positive breast cancer.Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse modelHaploinsufficient tumor suppressor genes.Alternative splicing promotes tumour aggressiveness and drug resistance in African American prostate cancer.Elevated SRPK1 lessens apoptosis in breast cancer cells through RBM4-regulated splicing events.Translating RNA sequencing into clinical diagnostics: opportunities and challenges.Estrogen receptor beta impacts hormone-induced alternative mRNA splicing in breast cancer cells.ISOexpresso: a web-based platform for isoform-level expression analysis in human cancerAlternative splicing of estrogen receptor alpha in hepatocellular carcinomaOncogene- and drug resistance-associated alternative exon usage in acute myeloid leukemia (AML).Expression of an Oncogenic BARD1 Splice Variant Impairs Homologous Recombination and Predicts Response to PARP-1 Inhibitor Therapy in Colon CancerSURVIV for survival analysis of mRNA isoform variation.Aberrant splicing of the DMP1-ARF-MDM2-p53 pathway in cancerQKI5-mediated alternative splicing of the histone variant macroH2A1 regulates gastric carcinogenesis.TGF-β1 Induces Polypyrimidine Tract-Binding Protein to Alter Fibroblasts Proliferation and Fibronectin Deposition in Keloid.Functional analysis reveals that RBM10 mutations contribute to lung adenocarcinoma pathogenesis by deregulating splicingAssociations between genetic variants in mRNA splicing-related genes and risk of lung cancer: a pathway-based analysis from published GWASs.Splicing factor ratio as an index of epithelial-mesenchymal transition and tumor aggressiveness in breast cancer.Cancer whole-genome sequencing: present and future.LINE-1 in cancer: multifaceted functions and potential clinical implications.A novel functional splice variant of AKT3 defined by analysis of alternative splice expression in HPV-positive oropharyngeal cancers.Alternative Splicing in CKD.Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.Splicing regulator SLU7 preserves survival of hepatocellular carcinoma cells and other solid tumors via oncogenic miR-17-92 cluster expression.Epigenetic regulation and anti-tumorigenic effects of SH2-containing protein tyrosine phosphatase 1 (SHP1) in human gastric cancer cells.Paracrine communication maximizes cellular response fidelity in wound signaling.The influence of SRPK1 on glioma apoptosis, metastasis, and angiogenesis through the PI3K/Akt signaling pathway under normoxia.Alternative splicing and cell survival: from tissue homeostasis to disease.Comprehensive transcriptome analysis using synthetic long-read sequencing reveals molecular co-association of distant splicing events.The Arkadia-ESRP2 axis suppresses tumor progression: analyses in clear-cell renal cell carcinomaAlternative splicing discriminates molecular subtypes and has prognostic impact in diffuse large B-cell lymphoma.
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Alternative splicing in cancer: implications for biology and therapy.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
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name
Alternative splicing in cancer: implications for biology and therapy.
@en
type
label
Alternative splicing in cancer: implications for biology and therapy.
@en
prefLabel
Alternative splicing in cancer: implications for biology and therapy.
@en
P2860
P356
P1433
P1476
Alternative splicing in cancer: implications for biology and therapy.
@en
P2093
P2860
P2888
P356
10.1038/ONC.2013.570
P407
P577
2014-01-20T00:00:00Z
P5875
P6179
1021719497