Ion channels and transporters in the development of drug resistance in cancer cells
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Sphaeropsidin A shows promising activity against drug-resistant cancer cells by targeting regulatory volume increaseMICU1 drives glycolysis and chemoresistance in ovarian cancer.Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs.Genome-wide microarray expression and genomic alterations by array-CGH analysis in neuroblastoma stem-like cells.Drug Efflux Transporters Are Overexpressed in Short-Term Tamoxifen-Induced MCF7 Breast Cancer Cells.Wittig derivatization of sesquiterpenoid polygodial leads to cytostatic agents with activity against drug resistant cancer cells and capable of pyrrolylation of primary aminesAntiproliferative Activity of T. welwitschii Extract on Jurkat T Cells In Vitro.Extracellular galectin-3 programs multidrug resistance through Na+/K+-ATPase and P-glycoprotein signaling.A three ion channel genes-based signature predicts prognosis of primary glioblastoma patients and reveals a chemotherapy sensitive subtype.Ion channels in cancer: future perspectives and clinical potential.Functions of volume-sensitive and calcium-activated chloride channels.Physiological role of taurine--from organism to organelle.Role of volume-regulated and calcium-activated anion channels in cell volume homeostasis, cancer and drug resistanceResistance to anticancer drugs permanently alters electrophoretic mobility of cancer cell lines.Protolichesterinic Acid, Isolated from the Lichen Cetraria islandica, Reduces LRRC8A Expression and Volume-Sensitive Release of Organic Osmolytes in Human Lung Epithelial Cancer Cells.Impact of intracellular ion channels on cancer development and progression.Acquired cisplatin resistance in human ovarian A2780 cancer cells correlates with shift in taurine homeostasis and ability to volume regulate.Downregulation of LRRC8A protects human ovarian and alveolar carcinoma cells against Cisplatin-induced expression of p53, MDM2, p21Waf1/Cip1, and Caspase-9/-3 activation.Tumor-reducing effect of the clinically used drug clofazimine in a SCID mouse model of pancreatic ductal adenocarcinoma.The effect of substrate stiffness on cancer cell volume homeostasis.In vitro evaluation of the enantiomeric R- and S-1,1'-binaphthyl-2,2'-diaminodichlorido-Pt(ii) complexes in human Burkitt lymphoma cells: emphasis on cellular accumulation, cytotoxicity, DNA binding, and ability to induce apoptosis.Characterization of Human Dermal Fibroblasts in Fabry Disease.Expression of Na+-K+-2Cl- cotransporter isoform 1 (NKCC1) predicts poor prognosis in lung adenocarcinoma and EGFR-mutated adenocarcinoma patients.Downregulation of Leucine-Rich Repeat-Containing 8A Limits Proliferation and Increases Sensitivity of Glioblastoma to Temozolomide and Carmustine.Facilitating the Cellular Accumulation of Pt-Based Chemotherapeutic Drugs
P2860
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P2860
Ion channels and transporters in the development of drug resistance in cancer cells
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article científic
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article scientifique
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articol științific
@ro
articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artículo científico
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name
Ion channels and transporters in the development of drug resistance in cancer cells
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type
label
Ion channels and transporters in the development of drug resistance in cancer cells
@en
prefLabel
Ion channels and transporters in the development of drug resistance in cancer cells
@en
P2860
P921
P356
P1476
Ion channels and transporters in the development of drug resistance in cancer cells
@en
P2093
Else K Hoffmann
Ian H Lambert
P2860
P304
P356
10.1098/RSTB.2013.0109
P407
P5008
P577
2014-02-03T00:00:00Z
2014-03-19T00:00:00Z