WW domain-containing oxidoreductase's role in myriad cancers: clinical significance and future implications.
about
The FHIT gene product: tumor suppressor and genome "caretaker"Tumor Suppressor WWOX Contributes to the Elimination of Tumorigenic Cells in Drosophila melanogasterTumor Suppressor Genes within Common Fragile Sites Are Active Players in the DNA Damage ResponseHYAL-2-WWOX-SMAD4 Signaling in Cell Death and Anticancer ResponsePleiotropic Functions of Tumor Suppressor WWOX in Normal and Cancer CellsVersatile communication strategies among tandem WW domain repeatsLong non-coding RNA PARTICLE bridges histone and DNA methylationWWOX at the crossroads of cancer, metabolic syndrome related traits and CNS pathologies.Loss of wwox expression in zebrafish embryos causes edema and alters Ca(2+) dynamicsWW domain-containing oxidoreductase in neuronal injury and neurological diseases.Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.Structural insights into the functional versatility of WW domain-containing oxidoreductase tumor suppressor.Reduced expression of the WW domain-containing oxidoreductase in human hematopoietic malignancies.Alteration of WWOX in human cancer: a clinical view.Role of WW domain proteins WWOX in development, prognosis, and treatment response of glioma.A new tumor suppressor lncRNA RP11-190D6.2 inhibits the proliferation, migration, and invasion of epithelial ovarian cancer cells.The common fragile site FRA16D gene product WWOX: roles in tumor suppression and genomic stability.Interplay between genetic and epigenetic factors governs common fragile site instability in cancer.Very large common fragile site genes and their potential role in cancer development.The fragile site WWOX gene and the developing brain.The tumor suppressor WW domain-containing oxidoreductase modulates cell metabolism.WWOX: a fragile tumor suppressor.WWOX, large common fragile site genes, and cancer.Tumor suppressor WWOX regulates glucose metabolism via HIF1α modulation.Functions and Epigenetic Regulation of Wwox in Bone Metastasis from Breast Carcinoma: Comparison with Primary Tumors.WWOX loss activates aerobic glycolysis.Common fragile sites (CFS) and extremely large CFS genes are targets for human papillomavirus integrations and chromosome rearrangements in oropharyngeal squamous cell carcinoma.PARTICLE triplexes cluster in the tumor suppressor WWOX and may extend throughout the human genome.WWOX guards genome stability by activating ATM.Tumor Suppressor WWOX inhibits osteosarcoma metastasis by modulating RUNX2 function.WWOX and p53 Dysregulation Synergize to Drive the Development of OsteosarcomaCurrent questions and controversies in chromosome fragile site research: does WWOX, the gene product of common fragile site FRA16D, have a passive or active role in cancer?Tumor suppressor WWOX moderates the mitochondrial respiratory complex.WWOX inhibits the invasion of lung cancer cells by downregulating RUNX2.WWOX controls hepatic HIF1α to suppress hepatocyte proliferation and neoplasia.Modeling WWOX Loss of Function : What Have We Learned?Somatic loss of WWOX is associated with TP53 perturbation in basal-like breast cancer
P2860
Q26830817-F2F46F52-5D76-4B7F-B8E4-484C4B4258D9Q27321940-1AB7423E-710C-4DCF-AC80-B9A25F9F1597Q28070247-738FA469-78B3-4DEF-9EE3-D3736E59BD77Q28079276-4D112A0A-C01D-442E-AA5E-12D4F79FA0DDQ28080922-4282CC08-8D86-414B-A7BC-02DD7621E85AQ28087599-09C1179C-C0FD-42A9-A9C0-174176951F84Q33687024-107C570F-7FD5-46BA-B92F-C6B11A4C0E5EQ34120466-9A94D7E3-B9F3-4F4A-BAC9-5D1B0F9083A3Q35032155-9027E5A0-82D5-4ECC-AD2F-EAF50D44A0E4Q35067919-8B680D29-2B9A-4246-8122-16EF508B42D0Q35097063-56D396D9-E77E-4D63-9BB6-8875B45A87CBQ35217707-C6504ED7-4095-4AA4-8D7D-DAAFF4A9C208Q36954576-683A88E2-945F-4955-91DA-B6A244FF84B1Q37071040-FCBAFE30-45A5-45E3-B5AC-5A68990A9EB6Q37071045-359DD93D-2D5D-44FB-9EF1-7E0D1A4C45CFQ37682885-744F7038-26A2-4B62-BE09-27601E71FA41Q38253201-CF37BAC1-978B-49FB-8D7B-4C1450121E55Q38258279-F2B6F2AD-4FCB-42AC-BEED-CC7C8BBFA0C9Q38258543-8F42E246-5393-4453-98D0-E6CBA615E4A4Q38270425-0680C28B-8CD1-468A-986B-91B75FF4CDE3Q38285824-99A4CC70-7D91-4311-975D-33327DDEB8BAQ38299692-7E4C3293-8353-441F-BCE4-9E305589A9D7Q38321093-36B82E2E-1341-44A2-9D25-71559F24CDFDQ38976539-485B1135-FC16-439A-A15D-EB83636BC458Q39065640-EB8C7B0D-7AC4-4AE3-9B69-76ABC7684762Q39679531-89B16D85-F0A5-4727-AEF6-E7871CE69C95Q40473479-FC6F0723-5913-4CF2-AE61-2524E433BD73Q41223344-D8743B01-D494-4BBE-BCCF-97E01E0D9B35Q41952743-29D45A6E-C2F3-45E2-9094-5384A9B49A91Q41991686-6C009486-EBF5-4A18-B004-BBBFD0FEF5E0Q42355620-078AEAB4-DA8C-4589-93F9-1752ED0BA4A1Q42367791-1CFE23D5-040E-43A8-9FB7-1B4FC6527863Q46666593-77D938FA-53AC-40B1-94FC-BE16AAEF53FDQ51068895-357DB767-082B-43B4-9D92-DA0FF8F59F34Q55003004-15FD585B-DBE2-46EE-8273-1E824CA58035Q58123045-8AB7EF11-091E-46CB-86AF-9F59345DC8A1Q58799648-F6181F90-89D1-49A8-9644-920A588CB1D8
P2860
WW domain-containing oxidoreductase's role in myriad cancers: clinical significance and future implications.
description
article científic
@ca
article scientifique
@fr
articol științific
@ro
articolo scientifico
@it
artigo científico
@gl
artigo científico
@pt
artigo científico
@pt-br
artikel ilmiah
@id
artikull shkencor
@sq
artículo científico
@es
name
WW domain-containing oxidoredu ...... cance and future implications.
@en
type
label
WW domain-containing oxidoredu ...... cance and future implications.
@en
prefLabel
WW domain-containing oxidoredu ...... cance and future implications.
@en
P2860
P356
P1476
WW domain-containing oxidoredu ...... cance and future implications.
@en
P2093
Aliza Gardenswartz
Rami I Aqeilan
P2860
P304
P356
10.1177/1535370213519213
P577
2014-02-07T00:00:00Z