Nuclear matrix, nuclear envelope and premature aging syndromes in a translational research perspective.
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Hallmarks of progeroid syndromes: lessons from mice and reprogrammed cellsMolecular insights into the premature aging disease progeriaPhysiological and Pathological Aging Affects Chromatin Dynamics, Structure and Function at the Nuclear EdgeDrug screening on Hutchinson Gilford progeria pluripotent stem cells reveals aminopyrimidines as new modulators of farnesylation.DNA repair defects and genome instability in Hutchinson-Gilford Progeria Syndrome.Methods to Monitor DNA Repair Defects and Genomic Instability in the Context of a Disrupted Nuclear Lamina.All-trans retinoic acid and rapamycin normalize Hutchinson Gilford progeria fibroblast phenotype.Antisense-Based Progerin Downregulation in HGPS-Like Patients' Cells.A High Throughput Phenotypic Screening reveals compounds that counteract premature osteogenic differentiation of HGPS iPS-derived mesenchymal stem cells.NF-κB activation impairs somatic cell reprogramming in ageing.Mitotic Dysfunction Associated with Aging Hallmarks.Low lamin A expression in lung adenocarcinoma cells from pleural effusions is a pejorative factor associated with high number of metastatic sites and poor Performance status.Nuclear matrix revisited?Novel LMNA mutations cause an aggressive atypical neonatal progeria without progerin accumulation.Biomechanical Strain Exacerbates Inflammation on a Progeria-on-a-Chip Model.MicroRNAs in hereditary and sporadic premature aging syndromes and other laminopathies.Nuclear envelope remodelling during human spermiogenesis involves somatic B-type lamins and a spermatid-specific B3 lamin isoform.An overview of treatment strategies for Hutchinson-Gilford Progeria syndrome.The involvement of the nuclear lamina in human and rodent spermiogenesis: a systematic review.Pathological modelling of pigmentation disorders associated with Hutchinson-Gilford Progeria Syndrome (HGPS) revealed an impaired melanogenesis pathway in iPS-derived melanocytes.
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P2860
Nuclear matrix, nuclear envelope and premature aging syndromes in a translational research perspective.
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article científic
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article scientifique
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articol științific
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articolo scientifico
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artigo científico
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artigo científico
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artigo científico
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artikel ilmiah
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artículo científico
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Nuclear matrix, nuclear envelo ...... lational research perspective.
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type
label
Nuclear matrix, nuclear envelo ...... lational research perspective.
@en
prefLabel
Nuclear matrix, nuclear envelo ...... lational research perspective.
@en
P2093
P50
P1476
Nuclear matrix, nuclear envelo ...... slational research perspective
@en
P2093
Elise Kaspi
Pierre Cau
Sabine Sigaudy
P304
P356
10.1016/J.SEMCDB.2014.03.021
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P577
2014-03-22T00:00:00Z