Feedback and redundancy in receptor tyrosine kinase signaling: relevance to cancer therapies.
about
Resistance to receptor tyrosine kinase inhibition in cancer: molecular mechanisms and therapeutic strategiesDual Inhibition of Topoisomerase II and Tyrosine Kinases by the Novel Bis-Fluoroquinolone Chalcone-Like Derivative HMNE3 in Human Pancreatic Cancer CellsIdentifying kinase dependency in cancer cells by integrating high-throughput drug screening and kinase inhibition dataLevel of FACT defines the transcriptional landscape and aggressive phenotype of breast cancer cells.Receptor tyrosine kinases modulate distinct transcriptional programs by differential usage of intracellular pathwaysA signaling visualization toolkit to support rational design of combination therapies and biomarker discovery: SiViT.Sensitivity of GBM cells to cAMP agonist-mediated apoptosis correlates with CD44 expression and agonist resistance with MAPK signaling.Gallic acid inhibition of Src-Stat3 signaling overcomes acquired resistance to EGF receptor tyrosine kinase inhibitors in advanced non-small cell lung cancer.A price to pay for tumor regression.Opportunities and challenges provided by crosstalk between signalling pathways in cancer.In vivo oncogenic conflict triggered by co-existing KRAS and EGFR activating mutations in lung adenocarcinoma.Targeting the HER Family with Pan-HER Effectively Overcomes Resistance to Cetuximab.Fgf3-Fgf4-cis: A new mouse line for studying Fgf functions during mouse development.Akt inhibition improves irinotecan treatment and prevents cell emergence by switching the senescence response to apoptosis.A melanoma subtype with intrinsic resistance to BRAF inhibition identified by receptor tyrosine kinases gene-driven classification.MYC and AMPK-Save Energy or Die!NF-κB as the main node of resistance to receptor tyrosine kinase inhibitors in triple-negative breast cancer.An essential role of CBL and CBL-B ubiquitin ligases in mammary stem cell maintenance.Benefits of Multifaceted Chemopreventives in the Suppression of the Oral Squamous Cell Carcinoma (OSCC) Tumorigenic Phenotype.Activation Status of Receptor Tyrosine Kinases as an Early Predictive Marker of Response to Chemotherapy in Osteosarcoma.Enhancing Virtual Screening Performance of Protein Kinases with Molecular Dynamics SimulationsNew insights into malignant cell survival mechanisms in medulloblastoma.Seeing the Forest for the Trees.Network dynamics-based cancer panel stratification for systemic prediction of anticancer drug response.Breast Cancer Cell Apoptosis is Synergistically Induced by Curcumin, Trastuzumab, and Glutathione Peroxidase-1 but Robustly Inhibited by Glial Cell Line-Derived Neurotrophic Factor.mTORC1 suppresses PIM3 expression via miR-33 encoded by the SREBP loci.High-throughput screening uncovers miRNAs enhancing glioblastoma cell susceptibility to tyrosine kinase inhibitors.Orthologous CRISPR-Cas9 enzymes for combinatorial genetic screens.A phosphokinome-based screen uncovers new drug synergies for cancer driven by liver-specific gain of nononcogenic receptor tyrosine kinases.Mechanisms of rapid cancer cell reprogramming initiated by targeted receptor tyrosine kinase inhibitors and inherent therapeutic vulnerabilities.Cognitive Computing to Guide Molecular-Based Therapy Selection: Steps Forward amid Abundant Need.The Role of Kinase Modulators in Cellular Senescence for Use in Cancer Treatment.Major Physiological Signaling Pathways in the Regulation of Cell Proliferation and Survival.
P2860
Q27004161-26D37B51-0E4F-42FF-8735-64AE504D3301Q28552765-DEDDE996-4956-4B9F-BB21-03AAA866B177Q30982375-6443D7CC-9E38-481E-B505-15B21B8BE418Q33591234-0DFA26CF-FB90-4CD7-8638-E717EF3D6412Q35669628-74D7EC9C-A0DE-4036-A322-606F031DF4F9Q36052565-073AD114-CB3C-4C90-8DF2-8B885E960855Q36209203-7A829FD6-8833-47DF-BDDC-6B22C3C3B315Q37688123-33CC44DC-06AD-4D1B-964C-AFC6F1DD12CDQ38431269-3128A8BA-6BF4-452B-9E41-A77ECB50278FQ38485894-6D8AFEE2-C862-4C78-A6E5-7DA159480828Q38738104-CF99155D-0E51-410D-8F90-2F2FAA13ACB6Q38757863-937087D7-1521-4978-8E22-44F591B6ED6DQ38811850-273CE7E7-7E6B-4053-BD60-7DA60BBF7E78Q38826343-D2E26273-F577-47C8-98F1-F232EA124C36Q38903238-B7B06C4A-0E15-4F0F-8F63-1ADFC5F57EAAQ39262984-DB9D00CE-502A-4947-8BF2-7E3E1BA157F2Q39400435-89A162E1-B89E-4F23-B227-F8E6ABFFAE63Q40374590-5199EDE3-8B23-4D83-86DA-A52ABD18ED41Q41070558-0285EC59-42EC-49C9-83FB-7FAB04D320ABQ41624093-C7C019EB-7E5A-4438-AD35-9148F3D3B843Q42320200-B100854D-B5FB-4A93-95E6-38F9525A834DQ42427245-E084E1EA-B423-41E8-8399-C9BF4303FB92Q43288671-6E55E24A-9E08-4BDF-9898-DF90D88B2A8BQ47155414-C9209853-8C99-4EC1-83D2-1765C10F0A4AQ47202764-F1A12855-B2E7-4BA7-B427-BD2E235DF4E4Q47352692-AC6B5B1B-3DEC-4336-A800-FB3FC3A4A0F5Q47606186-12DC081A-A801-4DCC-A254-658F7D1DD8F2Q48100849-D74C6BB7-D876-46EB-91A3-B3628F227CF1Q48321277-78CD4CA7-64F7-4AC3-822E-59A9649EA9B8Q49843607-8E0A9DA7-54C0-4358-B2EB-9CB23079B50FQ50059456-612891A8-69C7-46B3-8A41-FA426D5A605FQ51800912-B2F781E2-9C53-4D59-A028-591977D40941Q52713189-3B2BAF3C-6C77-462B-9703-E045C096F256
P2860
Feedback and redundancy in receptor tyrosine kinase signaling: relevance to cancer therapies.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
Feedback and redundancy in rec ...... relevance to cancer therapies.
@en
type
label
Feedback and redundancy in rec ...... relevance to cancer therapies.
@en
prefLabel
Feedback and redundancy in rec ...... relevance to cancer therapies.
@en
P1476
Feedback and redundancy in rec ...... relevance to cancer therapies.
@en
P304
P356
10.1016/J.TIBS.2014.08.010
P577
2014-09-16T00:00:00Z