Retrograde TrkAIII transport from ERGIC to ER: a re-localisation mechanism for oncogenic activity.
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Association of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents.TrkA is a binding partner of NPM-ALK that promotes the survival of ALK+ T-cell lymphoma.TRAIL induces pro-apoptotic crosstalk between the TRAIL-receptor signaling pathway and TrkAIII in SH-SY5Y cells, unveiling a potential therapeutic "Achilles heel" for the TrkAIII oncoprotein in neuroblastoma.TrkAIII signals endoplasmic reticulum stress to the mitochondria in neuroblastoma cells, resulting in glycolytic metabolic adaptation.The oncogenic neurotrophin receptor tropomyosin-related kinase variant, TrkAIII.
P2860
Retrograde TrkAIII transport from ERGIC to ER: a re-localisation mechanism for oncogenic activity.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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name
Retrograde TrkAIII transport f ...... hanism for oncogenic activity.
@en
type
label
Retrograde TrkAIII transport f ...... hanism for oncogenic activity.
@en
prefLabel
Retrograde TrkAIII transport f ...... hanism for oncogenic activity.
@en
P2093
P2860
P356
P1433
P1476
Retrograde TrkAIII transport f ...... chanism for oncogenic activity
@en
P2093
Lucia Cappabianca
Luciana Gneo
Pierdomenico Ruggeri
Rita Maccarone
P2860
P304
35636-35651
P356
10.18632/ONCOTARGET.5802
P407
P577
2015-11-01T00:00:00Z