Transcriptomic signature for drug-induced steatosis.

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Pathophysiology of cholestatic liver disease and its relevance for in vitro tests of hepatotoxicity.

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Transcriptomic signature for drug-induced steatosis.

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2015 nî lūn-bûn

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年學術文章

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2015年學術文章

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2015年學術文章

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name

Transcriptomic signature for drug-induced steatosis.

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type

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Transcriptomic signature for drug-induced steatosis.

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Transcriptomic signature for drug-induced steatosis.

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P1476

Transcriptomic signature for drug-induced steatosis.

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P2093

Regina Stöber

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P2860

Cryopreserved primary hepatocytes as a constantly available in vitro model for the evaluation of human and animal drug metabolism and enzyme induction.

Drug metabolizing enzyme induction pathways in experimental non-alcoholic steatohepatitis.

Nonalcoholic fatty liver disease: from steatosis to cirrhosis.

Primary hepatocytes: current understanding of the regulation of metabolic enzymes and transporter proteins, and pharmaceutical practice for the use of hepatocytes in metabolism, enzyme induction, transporter, clearance, and hepatotoxicity studies.

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.

Drug-induced liver steatosis and phospholipidosis: cell-based assays for early screening of drug candidates.

Mechanisms of amiodarone and valproic acid induced liver steatosis in mouse in vivo act as a template for other hepatotoxicity models.

Inhibition of mitochondrial beta-oxidation as a mechanism of hepatotoxicity.

Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells.

The rediscovery of HepG2 cells for prediction of drug induced liver injury (DILI).

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1259-1260

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scholarly article

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10.17179/EXCLI2015-758

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2015-12-21T00:00:00Z

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26862324

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transcriptome

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4743474

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Transcriptomic signature for drug-induced steatosis.

about

P2860

P2860

Transcriptomic signature for drug-induced steatosis.

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P1433

P1476

P2093

P2860

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P1476

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