Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma.
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Recent advances in understanding transcription termination by RNA polymerase IITranscriptional termination in mammals: Stopping the RNA polymerase II juggernautChimPipe: accurate detection of fusion genes and transcription-induced chimeras from RNA-seq data.Genomic aberrations frequently alter chromatin regulatory genes in chordoma.Histone gene replacement reveals a post-transcriptional role for H3K36 in maintaining metazoan transcriptome fidelity.Readthrough transcription: How are DoGs made and what do they do?Transcription-coupled changes to chromatin underpin gene silencing by transcriptional interference.A PWWP Domain of Histone-Lysine N-Methyltransferase NSD2 Binds to Dimethylated Lys-36 of Histone H3 and Regulates NSD2 Function at Chromatin.Overexpression of KLHL23 protein from read-through transcription of PHOSPHO2-KLHL23 in gastric cancer increases cell proliferation.Lessons from non-canonical splicingComplex chromosomal neighborhood effects determine the adaptive potential of a gene under selection.Alternative splicing: the pledge, the turn, and the prestige : The key role of alternative splicing in human biological systems.H3K36 methyltransferases as cancer drug targets: rationale and perspectives for inhibitor developmentShaping the cellular landscape with Set2/SETD2 methylation.A pan-cancer analysis of MYC-PVT1 reveals CNV-unmediated deregulation and poor prognosis in renal carcinoma.H3K36 Methylation Regulates Nutrient Stress Response in Saccharomyces cerevisiae by Enforcing Transcriptional Fidelity.Comparative analysis reveals genomic features of stress-induced transcriptional readthrough.The role of alternative splicing in cancer.Connections between Transcription Downstream of Genes and cis-SAGe Chimeric RNA.Characterization of H3.3K36M as a tool to study H3K36 methylation in cancer cells.Calcium signaling and transcription: elongation, DoGs, and eRNAs.Set2 methyltransferase facilitates cell cycle progression by maintaining transcriptional fidelity.Emerging Properties and Functional Consequences of Noncoding Transcription.Spurious transcription and its impact on cell function.--RNA Polymerase II Transcription Attenuation at the Yeast DNA Repair Gene, DEF1, Involves Sen1-Dependent and Polyadenylation Site-Dependent Termination.New chimeric RNAs in acute myeloid leukemia.HSV-1-induced disruption of transcription termination resembles a cellular stress response but selectively increases chromatin accessibility downstream of genes.Global isoform-specific transcript alterations and deregulated networks in clear cell renal cell carcinoma.Caution needs to be taken when assigning transcription start sites to ends of protein-coding genes: a rebuttal.Defective transcription elongation in a subset of cancers confers immunotherapy resistanceDoGFinder: a software for the discovery and quantification of readthrough transcripts from RNA-seq
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P2860
Pervasive transcription read-through promotes aberrant expression of oncogenes and RNA chimeras in renal carcinoma.
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年學術文章
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2015年學術文章
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2015年學術文章
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name
Pervasive transcription read-t ...... A chimeras in renal carcinoma.
@en
type
label
Pervasive transcription read-t ...... A chimeras in renal carcinoma.
@en
prefLabel
Pervasive transcription read-t ...... A chimeras in renal carcinoma.
@en
P2093
P2860
P50
P356
P1433
P1476
Pervasive transcription read-t ...... A chimeras in renal carcinoma.
@en
P2093
Filipa B Martins
Mafalda R Matos
Maria Carmo-Fonseca
P2860
P356
10.7554/ELIFE.09214
P407
P577
2015-11-17T00:00:00Z