Reconstructing the in vivo dynamics of hematopoietic stem cells from telomere length distributions
about
Should tissue structure suppress or amplify selection to minimize cancer risk?Accumulation of DNA damage in the aged hematopoietic stem cell compartmentClonal hematopoiesis, with and without candidate driver mutations, is common in the elderly.Hierarchical tissue organization as a general mechanism to limit the accumulation of somatic mutations.Telomeres open a window on stem cell division.Evidence for a pre-existing telomere deficit in non-clonal hematopoietic stem cells in patients with acute myeloid leukemia.The Cancer Stem Cell Fraction in Hierarchically Organized Tumors Can Be Estimated Using Mathematical Modeling and Patient-Specific Treatment Trajectories.DNA methylation in PRDM8 is indicative for dyskeratosis congenita.Extinction rates in tumour public goods gamesClonal dominance and transplantation dynamics in hematopoietic stem cell compartments.Telomeres and Telomerase in Hematopoietic Dysfunction: Prognostic Implications and Pharmacological Interventions.Presence of TERT Promoter Mutations is a Secondary Event and Associates with Elongated Telomere Length in Myxoid Liposarcomas.Response to the Editor: On the Growth of Hematopoietic Stem Cells and Childhood Leukemias.Variation of mutational burden in healthy human tissues suggests non-random strand segregation and allows measuring somatic mutation rates.Replicative cellular age distributions in compartmentalized tissuesReproductive history and blood cell telomere lengthPopulation dynamics of normal human blood inferred from somatic mutations
P2860
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P2860
Reconstructing the in vivo dynamics of hematopoietic stem cells from telomere length distributions
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年學術文章
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2015年學術文章
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2015年學術文章
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name
Reconstructing the in vivo dyn ...... telomere length distributions
@en
type
label
Reconstructing the in vivo dyn ...... telomere length distributions
@en
prefLabel
Reconstructing the in vivo dyn ...... telomere length distributions
@en
P2093
P2860
P356
P1433
P1476
Reconstructing the in vivo dyn ...... telomere length distributions
@en
P2093
Arne Traulsen
Fabian Beier
Lisa Lassay
Sebastian Hummel
Stefan Balabanov
Thorsten Orlikowsky
Tim H Brümmendorf
P2860
P356
10.7554/ELIFE.08687
P407
P577
2015-10-15T00:00:00Z