Cartilage preservation by inhibition of Janus kinase 3 in two rodent models of rheumatoid arthritis.
about
Janus kinases in immune cell signalingJakinibs: a new class of kinase inhibitors in cancer and autoimmune diseaseTherapeutic targeting of Janus kinasesAnimal Models of Bone Loss in Inflammatory Arthritis: from Cytokines in the Bench to Novel Treatments for Bone Loss in the Bedside-a Comprehensive ReviewCellular targeting in autoimmunityAdalimumab for the treatment of rheumatoid arthritisTyrosine kinase inhibitors for the treatment of rheumatoid arthritisEffects of VLA-1 Blockade on Experimental Inflammation in MiceInhibition of the signalling kinase JAK3 alleviates inflammation in monoarthritic rats.Anti-inflammatory activity and neutrophil reductions mediated by the JAK1/JAK3 inhibitor, CP-690,550, in rat adjuvant-induced arthritis.TNFα and IFNγ synergistically enhance transcriptional activation of CXCL10 in human airway smooth muscle cells via STAT-1, NF-κB, and the transcriptional coactivator CREB-binding protein.Modulation of innate and adaptive immune responses by tofacitinib (CP-690,550).Tofacitinib for the treatment of rheumatoid arthritis.Cytokine-modulating strategies and newer cytokine targets for arthritis therapy.Effects of sulfasalazine and tofacitinib on the protein profile of articular chondrocytes.A validated LC-MS/MS assay for simultaneous quantification of methotrexate and tofacitinib in rat plasma: application to a pharmacokinetic study.Development and validation of a RP-HPLC method for the quantitation of tofacitinib in rat plasma and its application to a pharmacokinetic study.Janus kinase 3: the controller and the controlledAn LC-MS/MS method for rapid and sensitive high-throughput simultaneous determination of various protein kinase inhibitors in human plasma.Kinase inhibitors: a new class of antirheumatic drugsJAK Kinases in Health and Disease: An UpdatePeriodontitis increases rheumatic factor serum levels and citrullinated proteins in gingival tissues and alter cytokine balance in arthritic rats.Simultaneous inhibition of JAK and SYK kinases ameliorates chronic and destructive arthritis in mice.Inhibition of VEGFR-2 reverses type 1 diabetes in NOD mice by abrogating insulitis and restoring islet functionKinase inhibitors for the treatment of inflammatory and autoimmune disorders.Recent advances in neutralizing the IL-6 pathway in arthritis.CP-690550 Treatment Ameliorates Established Disease and Provides Long-Term Therapeutic Effects in an SKG Arthritis Model."Go upstream, young man": lessons learned from the p38 saga.Reversal of CD8 T-cell-mediated mucocutaneous graft-versus-host-like disease by the JAK inhibitor tofacitinib.Development of small-molecule therapies for autoimmune diseases.Targeting kinases for the treatment of inflammatory diseases.JAK inhibitor tofacitinib for treating rheumatoid arthritis: from basic to clinical.A pharmacokinetic and clinical assessment of tofacitinib for the treatment of rheumatoid arthritis.Tofacitinib: a review of its use in adult patients with rheumatoid arthritis.Current immunotherapy in rheumatoid arthritis.Targeting the Janus kinases in rheumatoid arthritis: focus on tofacitinib.Protein kinase inhibitors in the treatment of inflammatory and autoimmune diseases.Old and new therapeutics for Rheumatoid Arthritis: in vivo models and drug development.Tofacitinib for the treatment of psoriasis.Effects of tofacitinib on nucleic acid metabolism in human articular chondrocytes.
P2860
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P2860
Cartilage preservation by inhibition of Janus kinase 3 in two rodent models of rheumatoid arthritis.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Cartilage preservation by inhi ...... odels of rheumatoid arthritis.
@en
type
label
Cartilage preservation by inhi ...... odels of rheumatoid arthritis.
@en
prefLabel
Cartilage preservation by inhi ...... odels of rheumatoid arthritis.
@en
P2093
P2860
P356
P1476
Cartilage preservation by inhi ...... odels of rheumatoid arthritis.
@en
P2093
Anthony J Milici
Elizabeth M Kudlacz
Laurent Audoly
Paul Changelian
Samuel Zwillich
P2860
P2888
P356
10.1186/AR2365
P577
2008-01-30T00:00:00Z
P5875
P6179
1016032636