Constitutive and chemokine-dependent internalization and recycling of CXCR7 in breast cancer cells to degrade chemokine ligands.
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Opposing roles of CXCR4 and CXCR7 in breast cancer metastasis.Carboxy-terminus of CXCR7 regulates receptor localization and functionUbiquitination of CXCR7 controls receptor traffickingThe chemokine receptor CCR1 is constitutively active, which leads to G protein-independent, β-arrestin-mediated internalizationCXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunityCollective cell migration in developmentDiversity and Inter-Connections in the CXCR4 Chemokine Receptor/Ligand Family: Molecular PerspectivesMIF and CXCL12 in Cardiovascular Diseases: Functional Differences and SimilaritiesChemokines and their receptors in AtherosclerosisEndocytic trafficking of chemokine receptorsCXCR7 protein expression in human adult brain and differentiated neuronsCXCR4, but not CXCR7, discriminates metastatic behavior in non-small cell lung cancer cellsRapid generation of multiplexed cell cocultures using acoustic droplet ejection followed by aqueous two-phase exclusion patterning.CXCL12-induced monocyte-endothelial interactions promote lymphocyte transmigration across an in vitro blood-brain barrierCXCR4 drives the metastatic phenotype in breast cancer through induction of CXCR2 and activation of MEK and PI3K pathwaysSecreted CXCL12 (SDF-1) forms dimers under physiological conditions.Polarization and migration in the zebrafish posterior lateral line system.Microfluidic source-sink model reveals effects of biophysically distinct CXCL12 isoforms in breast cancer chemotaxisCXCR7 controls competition for recruitment of β-arrestin 2 in cells expressing both CXCR4 and CXCR7.CXCR7 expression disrupts endothelial cell homeostasis and causes ligand-dependent invasion.Emerging concepts and approaches for chemokine-receptor drug discovery.Inhibition of CXCL12/CXCR4 axis as a potential targeted therapy of advanced gastric carcinomaC-X-C motif chemokine 12/C-X-C chemokine receptor type 7 signaling regulates breast cancer growth and metastasis by modulating the tumor microenvironment.Effects of the chemokine CXCL12 and combined internalization of its receptors CXCR4 and CXCR7 in human MCF-7 breast cancer cells.Differential estrogen-regulation of CXCL12 chemokine receptors, CXCR4 and CXCR7, contributes to the growth effect of estrogens in breast cancer cellsMicrofluidic platform for chemotaxis in gradients formed by CXCL12 source-sink cells.Higher plasma CXCL12 levels predict incident myocardial infarction and death in chronic kidney disease: findings from the Chronic Renal Insufficiency Cohort study.The chemokine receptor CXCR7 interacts with EGFR to promote breast cancer cell proliferation.Involvement of the CXCR7/CXCR4/CXCL12 axis in the malignant progression of human neuroblastoma.Imaging CXCL12-CXCR4 signaling in ovarian cancer therapy.Expression and functional heterogeneity of chemokine receptors CXCR4 and CXCR7 in primary patient-derived glioblastoma cells.Near-infrared molecular imaging of tumors via chemokine receptors CXCR4 and CXCR7.In vivo imaging of ligand receptor binding with Gaussia luciferase complementation.The CXCR7 chemokine receptor promotes B-cell retention in the splenic marginal zone and serves as a sink for CXCL12.Noninvasive imaging reveals inhibition of ovarian cancer by targeting CXCL12-CXCR4Endothelial CXCR7 regulates breast cancer metastasisScavenging of CXCL12 by CXCR7 promotes tumor growth and metastasis of CXCR4-positive breast cancer cells.Mathematical Model of the Firefly Luciferase Complementation Assay Reveals a Non-Linear Relationship between the Detected Luminescence and the Affinity of the Protein Pair Being AnalyzedBuilding the posterior lateral line system in zebrafish.A Preclinical Model of Inflammatory Breast Cancer to Study the Involvement of CXCR4 and ACKR3 in the Metastatic Process.
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Constitutive and chemokine-dependent internalization and recycling of CXCR7 in breast cancer cells to degrade chemokine ligands.
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
2010年學術文章
@zh
2010年學術文章
@zh-hant
name
Constitutive and chemokine-dep ...... to degrade chemokine ligands.
@en
type
label
Constitutive and chemokine-dep ...... to degrade chemokine ligands.
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prefLabel
Constitutive and chemokine-dep ...... to degrade chemokine ligands.
@en
P2093
P2860
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Constitutive and chemokine-dep ...... to degrade chemokine ligands.
@en
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P2860
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P304
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10.1038/ONC.2010.212
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P577
2010-06-07T00:00:00Z
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P6179
1042990671