Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export. - Wikidata - wikimedia - TriplyDB

Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export.

Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export.

http://www.wikidata.org/entity/Q38275088

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Multidrug resistance proteins (MRPs/ABCCs) in cancer chemotherapy and genetic diseases Role of MRP transporters in regulating antimicrobial drug inefficacy and oxidative stress-induced pathogenesis during HIV-1 and TB infections Multidrug Resistance Proteins (MRPs) and Cancer Therapy Tissue distribution and induction of human multidrug resistant protein 3 Delayed mechanism for induction of gamma-glutamylcysteine synthetase heavy subunit mRNA stability by oxidative stress involving p38 mitogen-activated protein kinase signaling Inhibitory effect of the reversal agents V-104, GF120918 and Pluronic L61 on MDR1 Pgp-, MRP1- and MRP2-mediated transport Montelukast is a potent and durable inhibitor of multidrug resistance protein 2-mediated efflux of taxol and saquinavir Sensitization of cells overexpressing multidrug-resistant proteins by pluronic P85.Both P-gp and MRP2 mediate transport of Lopinavir, a protease inhibitor The MRP family of drug efflux pumps.ABC of oral bioavailability: transporters as gatekeepers in the gut.Exploring the structure-activity relationships of ABCC2 modulators using a screening approach.The ABC transporters MDR1 and MRP2: multiple functions in disposition of xenobiotics and drug resistance.Modulation of oral drug bioavailability: from preclinical mechanism to therapeutic application.On the putative co-transport of drugs by multidrug resistance proteins.Transmembrane transport of endo- and xenobiotics by mammalian ATP-binding cassette multidrug resistance proteins.Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition.Molecular pharmacokinetics of catharanthus (vinca) alkaloids.Transporters in the intestine limiting drug and toxin absorption.Genetic and biochemical study of dual hereditary jaundice: Dubin-Johnson and Gilbert's syndromes. Haplotyping and founder effect of deletion in ABCC2 Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.Plasma membrane glutathione transporters and their roles in cell physiology and pathophysiology Human multidrug resistance protein 7 (ABCC10) is a resistance factor for nucleoside analogues and epothilone B.ABC drug transporters and immunity: novel therapeutic targets in autoimmunity and cancer.Multidrug resistance in the chronic lymphoproliferative disorders.Renal membrane transport of glutathione in toxicology and disease.Multidrug resistance associated proteins in multidrug resistance.Intestinal transporters for endogenic and pharmaceutical organic anions: the challenges of deriving in-vitro kinetic parameters for the prediction of clinically relevant drug-drug interactions.In vitro methods to support transporter evaluation in drug discovery and development.Renal transport of organic anions and cations.Interaction of the efflux transporters ABCB1 and ABCG2 with imatinib, nilotinib, and dasatinib.New insights in the biology of ABC transporters ABCC2 and ABCC3: impact on drug disposition.Renal Drug Transporters and Drug Interactions.Phase I and II metabolism and MRP2-mediated export of bosentan in a MDCKII-OATP1B1-CYP3A4-UGT1A1-MRP2 quadruple-transfected cell line.Functional characterization of ABCC2 promoter polymorphisms and allele-specific expression.Role of the plasma membrane leaflets in drug uptake and multidrug resistance.Effect of COPD treatments on MRP1-mediated transport in bronchial epithelial cells.Indomethacin induces apoptosis via a MRP1-dependent mechanism in doxorubicin-resistant small-cell lung cancer cells overexpressing MRP1.Mrp2 is involved in benzylpenicillin-induced choleresis.Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2).

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P2860

Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export.

http://www.wikidata.org/entity/Q38275088

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2000 nî lūn-bûn

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2000年の論文

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2000年学术文章

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2000年学术文章

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Vinblastine and sulfinpyrazone ...... iated with glutathione export.

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Vinblastine and sulfinpyrazone ...... iated with glutathione export.

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Vinblastine and sulfinpyrazone ...... iated with glutathione export.

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British Journal of Cancer

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Vinblastine and sulfinpyrazone ...... iated with glutathione export.

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P2093

Beijnen J

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Borst P

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Evers R

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Lankelma J

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Sparidans R

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Wielinga PR

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de Haas M

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P2860

Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA

Interactions of the human multidrug resistance proteins MRP1 and MRP2 with organic anions

ABC transporters: from microorganisms to man

A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome

cDNA cloning of the hepatocyte canalicular isoform of the multidrug resistance protein, cMrp, reveals a novel conjugate export pump deficient in hyperbilirubinemic mutant rats

Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): evidence for cotransport with reduced glutathione

Congenital jaundice in rats with a mutation in a multidrug resistance-associated protein gene

Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein

The ATP-dependent glutathione S-conjugate export pump.

The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump.

P2888

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375-383

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10.1054/BJOC.2000.1262

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1026350908

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10917554

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multiple drug resistance

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2374564

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