The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts.
about
EWS/FLI mediates transcriptional repression via NKX2.2 during oncogenic transformation in Ewing's sarcomaCD99 inhibits neural differentiation of human Ewing sarcoma cells and thereby contributes to oncogenesisBMI-1 promotes ewing sarcoma tumorigenicity independent of CDKN2A repressionOn the epistemological crisis in genomicsWhat Do We Know about the Role of miRNAs in Pediatric Sarcoma?Sequencing Overview of Ewing Sarcoma: A Journey across Genomic, Epigenomic and Transcriptomic LandscapesMolecular mechanisms of ETS transcription factor-mediated tumorigenesisChildren's Oncology Group's 2013 blueprint for research: bone tumorsExploring the surfaceome of Ewing sarcoma identifies a new and unique therapeutic targetSignature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcomaClinical and biochemical function of polymorphic NR0B1 GGAA-microsatellites in Ewing sarcoma: a report from the Children's Oncology GroupFusion transcriptome profiling provides insights into alveolar rhabdomyosarcoma.Mining published lists of cancer related microarray experiments: identification of a gene expression signature having a critical role in cell-cycle control.Investigation of the insulin-like growth factor-1 signaling pathway in localized Ewing sarcoma: a report from the Children's Oncology Group.EWS/FLI1 oncogene activates caspase 3 transcription and triggers apoptosis in vivo.C/EBPβ-1 promotes transformation and chemoresistance in Ewing sarcoma cellsIs There a Predisposition Gene for Ewing's Sarcoma?Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse modelCoordinated control of senescence by lncRNA and a novel T-box3 co-repressor complex.Identification and validation of genes involved in cervical tumourigenesis.The oncogenic TLS-ERG fusion protein exerts different effects in hematopoietic cells and fibroblasts.Modeling initiation of Ewing sarcoma in human neural crest cells.Hypoxia modulates EWS-FLI1 transcriptional signature and enhances the malignant properties of Ewing's sarcoma cells in vitro.The TET family of proteins: functions and roles in disease.Animal models of soft-tissue sarcoma.Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's Sarcoma.Primary spinal intradural mesenchymal chondrosarcoma with detection of fusion gene HEY1-NCOA2: A paediatric case report and review of the literature.Molecular dissection of the mechanism by which EWS/FLI expression compromises actin cytoskeletal integrity and cell adhesion in Ewing sarcoma.EWS-FLI1 induces developmental abnormalities and accelerates sarcoma formation in a transgenic mouse model.Cell Cycle Deregulation in Ewing's Sarcoma PathogenesisProtein tyrosine phosphatases as potential therapeutic targets.Reversible inhibition of lysine specific demethylase 1 is a novel anti-tumor strategy for poorly differentiated endometrial carcinoma.Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma.The ETS gene ETV4 is required for anchorage-independent growth and a cell proliferation gene expression program in PC3 prostate cells.Review of therapeutic strategies for osteosarcoma, chondrosarcoma, and Ewing's sarcoma.BCL11B is up-regulated by EWS/FLI and contributes to the transformed phenotype in Ewing sarcomaEZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation.PIM3 proto-oncogene kinase is a common transcriptional target of divergent EWS/ETS oncoproteinsEpigenetic reprogramming and re-differentiation of a Ewing sarcoma cell linePromiscuous partnerships in Ewing's sarcoma.
P2860
Q21144325-4177404D-7470-4B3C-8B5F-D1CD4B6999E4Q24642797-8E0AB084-D641-4D10-BCDE-2C9AD40AE428Q24650619-A8BEC2AA-CA89-4F3B-9536-463FB2F0C915Q24652735-24C8DAAD-CDB3-4059-9D24-48948904DE97Q26800124-A50EBAAF-B8A0-4F2D-90DB-A80295DA4E1AQ26801785-D0D76B95-4702-43E3-9D16-7EEB3D73D2B5Q26829833-71280424-22AB-4C08-B16F-2F9527D98B5AQ27027664-215F46F4-6C28-4B5B-889D-CFB9E1C4F14BQ27317164-FDD646C1-319B-4568-8F7B-2E1C0520ADF2Q28469179-C3689B69-D3FA-4389-A843-3FD6A51BF81BQ28541625-F862949B-DAE3-45CE-B7E5-67AECC2373F1Q30275551-2BC5D303-014E-4198-A00F-2482C748AFC5Q33229361-6C0DB90A-9E00-4F18-B14A-B7B2EEFD20F5Q33559559-8C81A407-8B46-4A47-913A-04E98135260AQ33638434-CA5DFD12-B70E-436D-8689-D27B183514A9Q33688502-2B07B1E3-96A9-431E-B667-DBBB9E7E0A4CQ33726883-8C3177CE-0BF0-457C-9A71-CCA19E7C0553Q33798299-A06E1BEB-5608-4BCD-BDC1-14115ECDB4DCQ33808862-0EFB1E7A-7981-46E6-8EB7-3DB79AB35ADDQ33825832-9CEB2EB2-29CA-4DA3-87B1-33FF1566D7AEQ33884178-26996C7D-A6CB-4EAF-8F82-77DC3585C396Q33894979-42C58AE1-F23F-4FC9-9507-7E0688A39CD2Q33908885-2E03C250-5DD3-471E-B926-56F8875825A9Q33999337-1EC21042-E3EB-43D2-AAF0-5B77C363B14DQ34098113-A829E46F-B9D2-455A-8DBD-7D6A6D80289AQ34109415-694DE8A6-8E27-4810-B615-0C0E04C3778AQ34141858-E7E910B7-DDDA-4AAD-B285-604B30110293Q34166817-757A0FB8-7A85-48F9-A5D9-5FA395FA9418Q34206278-85DA1B1E-6C01-456D-8BCB-F9A60A0DD87CQ34260723-FB302E9C-49F1-4122-A7FD-4CD9B121DFA5Q34295063-1CA4A9F1-019D-4BB7-AE23-C9CABA4118C3Q34340537-602296C9-7C9F-42B0-82C0-82AB9880DA05Q34492346-C7274E0B-F63E-4391-8558-6E46409E1EF7Q34613397-3C49CB59-2F11-487F-9E47-BE55EF99E776Q34631306-E3B4B7F5-5BC2-4A97-9E38-FB74638467B7Q34635079-9AF4060C-C231-4AA3-A8EB-4C2DC3866DEAQ34963463-805FB8F8-D09C-4D57-9122-2B29D716DA45Q35002393-271D52C5-C4B5-4C41-A078-7E0B8240A92EQ35158389-DF11D044-80CC-4249-9CB9-FCF3EE10918FQ35188770-18C6DADD-76BE-47AE-B26E-4FD193D7AD0B
P2860
The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
The Ewing's sarcoma oncoprotei ...... in primary human fibroblasts.
@en
type
label
The Ewing's sarcoma oncoprotei ...... in primary human fibroblasts.
@en
prefLabel
The Ewing's sarcoma oncoprotei ...... in primary human fibroblasts.
@en
P2093
P1433
P1476
The Ewing's sarcoma oncoprotei ...... in primary human fibroblasts.
@en
P2093
Caroline S Dacwag
Stephen L Lessnick
Todd R Golub
P304
P356
10.1016/S1535-6108(02)00056-9
P577
2002-05-01T00:00:00Z