Leptin is required for fibrogenic responses induced by thioacetamide in the murine liver.
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Nonalcoholic fatty liver diseaseLeptin induces an inflammatory phenotype in lean Wistar ratsAdiponectin activation of AMPK disrupts leptin-mediated hepatic fibrosis via suppressors of cytokine signaling (SOCS-3)GATA binding protein 3 is correlated with leptin regulation of PPARγ1 in hepatic stellate cellsThe effects of diet composition on body fat and hepatic steatosis in an animal (Peromyscus californicus) model of the metabolic syndrome.Leptin induces increased alpha2(I) collagen gene expression in cultured rat hepatic stellate cells.Leptin as a novel profibrogenic cytokine in hepatic stellate cells: mitogenesis and inhibition of apoptosis mediated by extracellular regulated kinase (Erk) and Akt phosphorylation.Leptin increases tissue inhibitor of metalloproteinase I (TIMP-1) gene expression by a specificity protein 1/signal transducer and activator of transcription 3 mechanism.Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway.Cannabidiol improves brain and liver function in a fulminant hepatic failure-induced model of hepatic encephalopathy in miceAnimal models for the study of liver fibrosis: new insights from knockout mouse models.Micro-RNA 21 inhibition of SMAD7 enhances fibrogenesis via leptin-mediated NADPH oxidase in experimental and human nonalcoholic steatohepatitisAdipokines levels are associated with the severity of liver disease in patients with alcoholic cirrhosisHepatic fibrogenesis requires sympathetic neurotransmitters.Cytokines and the pathogenesis of non-alcoholic steatohepatitis.p38 mitogen-activated protein kinase and liver X receptor-α mediate the leptin effect on sterol regulatory element binding protein-1c expression in hepatic stellate cellsCytokines and STATs in Liver Fibrosis.Mouse models in non-alcoholic fatty liver disease and steatohepatitis research.Adiponectin-derived active peptide ADP355 exerts anti-inflammatory and anti-fibrotic activities in thioacetamide-induced liver injuryOsteopontin is a proximal effector of leptin-mediated non-alcoholic steatohepatitis (NASH) fibrosis.The β-catenin pathway contributes to the effects of leptin on SREBP-1c expression in rat hepatic stellate cells and liver fibrosisPrevention of hepatic fibrosis in a murine model of metabolic syndrome with nonalcoholic steatohepatitis.Risk factors and mechanisms of non-alcoholic steatohepatitisOxidative and nitrosative stress and fibrogenic response.Non alcoholic fatty liver disease and metabolic syndrome.Association between leptin, metabolic factors and liver histology in patients with chronic hepatitis CExperimental liver fibrosis research: update on animal models, legal issues and translational aspects.Kupffer cells mediate leptin-induced liver fibrosisCrosstalk between angiogenesis, cytokeratin-18, and insulin resistance in the progression of non-alcoholic steatohepatitis.Serum levels of apoptosis inhibitor of macrophage are associated with hepatic fibrosis in patients with chronic hepatitis C.Update on the pathophysiology of liver fibrosis.Animal models of alcoholic liver disease.Acetaldehyde increases endogenous adiponectin and fibrogenesis in hepatic stellate cells but exogenous adiponectin inhibits fibrogenesis.Role of adipocytokines in hepatic fibrogenesis.Leptin is a coactivator of TGF-beta in unilateral ureteral obstructive kidney disease.Glucagon-like peptide-1 receptor agonism improves metabolic, biochemical, and histopathological indices of nonalcoholic steatohepatitis in mice.Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis.Leptin's regulation of obesity-induced cardiac extracellular matrix remodeling.Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin.Alleviation of CCl4-induced cirrhosis in rats by tetramethylpyrazine is associated with downregulation of leptin and TGF-beta1 pathway.
P2860
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P2860
Leptin is required for fibrogenic responses induced by thioacetamide in the murine liver.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Leptin is required for fibrogenic responses induced by thioacetamide in the murine liver.
@en
type
label
Leptin is required for fibrogenic responses induced by thioacetamide in the murine liver.
@en
prefLabel
Leptin is required for fibrogenic responses induced by thioacetamide in the murine liver.
@en
P2093
P356
P1433
P1476
Leptin is required for fibrogenic responses induced by thioacetamide in the murine liver.
@en
P2093
Hajime Honda
Kenichi Ikejima
Miyoko Hirose
Mutsuko Yoshikawa
Nobuhiro Sato
Nobuyuki Enomoto
Tsuneo Kitamura
Yoshiyuki Takei
P356
10.1053/JHEP.2002.33684
P407
P577
2002-07-01T00:00:00Z