Retroviral delivery of connexin genes to human breast tumor cells inhibits in vivo tumor growth by a mechanism that is independent of significant gap junctional intercellular communication.
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Connexins: a myriad of functions extending beyond assembly of gap junction channelsConnexin 43 mediated gap junctional communication enhances breast tumor cell diapedesis in cultureReduced expression of multiple gap junction proteins is a feature of cervical dysplasia.Gap junctions in inherited human disorders of the central nervous system.Gap junctionsGap junction and hemichannel-independent actions of connexins on cell and tissue functions--an updateConnexin's Connection in Breast Cancer Growth and ProgressionConnexin43 functions as a novel interacting partner of heat shock cognate protein 70The gap junction-independent tumor-suppressing effect of connexin 43Caveolin-1 and -2 interact with connexin43 and regulate gap junctional intercellular communication in keratinocytesPannexin1 and pannexin3 delivery, cell surface dynamics, and cytoskeletal interactionsMatricellular protein CCN3 (NOV) regulates actin cytoskeleton reorganization.IRES-mediated translation of the carboxy-terminal domain of the horizontal cell specific connexin Cx55.5 in vivo and in vitro.E-cadherin and β-catenin adhesion proteins correlate positively with connexins in colorectal cancer.Undetectable and Decreased Expression of KIAA1949 (Phostensin) Encoded on Chromosome 6p21.33 in Human Breast Cancers Revealed by Transcriptome Analysis.Connexin43-dependent mechanism modulates renin secretion and hypertensionA p-Median approach for predicting drug response in tumour cells.Treatment with connexin 46 siRNA suppresses the growth of human Y79 retinoblastoma cell xenografts in vivoIntercellular redistribution of cAMP underlies selective suppression of cancer cell growth by connexin26.Inhibitory effects of osteoblasts and increased bone formation on myeloma in novel culture systems and a myelomatous mouse modelA novel role of gap junction connexin46 protein to protect breast tumors from hypoxia.Cx31.1 acts as a tumour suppressor in non-small cell lung cancer (NSCLC) cell lines through inhibition of cell proliferation and metastasisTargeting connexin 43 with α-connexin carboxyl-terminal (ACT1) peptide enhances the activity of the targeted inhibitors, tamoxifen and lapatinib, in breast cancer: clinical implication for ACT1Gap junction- and hemichannel-independent actions of connexinsRegulation of gap junctions by tyrosine protein kinases.Anti-angiogenesis therapy and gap junction inhibition reduce MDA-MB-231 breast cancer cell invasion and metastasis in vitro and in vivo.Connexin and pannexin channels in cancer.Biological role of connexin intercellular channels and hemichannelsInteraction of Cx43 with Hsc70 regulates G1/S transition through CDK inhibitor p27Cx26 knockout predisposes the mammary gland to primary mammary tumors in a DMBA-induced mouse model of breast cancerKruppel-like factor 4 signals through microRNA-206 to promote tumor initiation and cell survival.Induction of Apoptosis by PQ1, a Gap Junction Enhancer that Upregulates Connexin 43 and Activates the MAPK Signaling Pathway in Mammary Carcinoma CellsStaphylococcus aureus-derived peptidoglycan induces Cx43 expression and functional gap junction intercellular communication in microglia.Molecular mechanism underlying differential apoptosis between human melanoma cell lines UACC903 and UACC903(+6) revealed by mitochondria-focused cDNA microarrays.Polarity proteins as regulators of cell junction complexes: implications for breast cancer.The stage-specific function of gap junctions during tumourigenesis.Glial connexins and gap junctions in CNS inflammation and disease.Array analysis of gene expression in connexin-43 null astrocytes.Expressing connexin 43 in breast cancer cells reduces their metastasis to lungs.Connexin43 increases the sensitivity of prostate cancer cells to TNFalpha-induced apoptosis.
P2860
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P2860
Retroviral delivery of connexin genes to human breast tumor cells inhibits in vivo tumor growth by a mechanism that is independent of significant gap junctional intercellular communication.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年学术文章
@wuu
2002年学术文章
@zh-cn
2002年学术文章
@zh-hans
2002年学术文章
@zh-my
2002年学术文章
@zh-sg
2002年學術文章
@yue
2002年學術文章
@zh
2002年學術文章
@zh-hant
name
Retroviral delivery of connexi ...... l intercellular communication.
@en
type
label
Retroviral delivery of connexi ...... l intercellular communication.
@en
prefLabel
Retroviral delivery of connexi ...... l intercellular communication.
@en
P2093
P2860
P356
P1476
Retroviral delivery of connexi ...... l intercellular communication.
@en
P2093
Daniel J Belliveau
Heather Curtis
Jacques Galipeau
Moulay A Alaoui-Jamali
Taiqi Wang
P2860
P304
29132-29138
P356
10.1074/JBC.M200797200
P407
P50
P577
2002-05-31T00:00:00Z