Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors.
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Role of RUNX2 in Breast CarcinogenesisOsteoinduction of human mesenchymal stem cells by bioactive composite scaffolds without supplemental osteogenic growth factorsGenome-wide exploration of miRNA function in mammalian muscle cell differentiation.Spatial and temporal analysis of gene expression during growth and fusion of the mouse facial prominences.Digital expression profiling identifies RUNX2, CDC5L, MDM2, RECQL4, and CDK4 as potential predictive biomarkers for neo-adjuvant chemotherapy response in paediatric osteosarcoma.Down-regulation of type I Runx2 mediated by dexamethasone is required for 3T3-L1 adipogenesis.Estrogen improves the proliferation and differentiation of hBMSCs derived from postmenopausal osteoporosis through notch signaling pathway.The gene for aromatase, a rate-limiting enzyme for local estrogen biosynthesis, is a downstream target gene of Runx2 in skeletal tissues.The osteogenic transcription factor Runx2 regulates components of the fibroblast growth factor/proteoglycan signaling axis in osteoblastsSynergistically enhanced osteogenic differentiation of human mesenchymal stem cells by culture on nanostructured surfaces with induction mediaGPR30 deficiency causes increased bone mass, mineralization, and growth plate proliferative activity in male mice.Cytosolic phospholipase A2 and lysophospholipids in tumor angiogenesisMonocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation.Investigating the role of FGF18 in the cultivation and osteogenic differentiation of mesenchymal stem cellsThe Role of RUNX2 in Osteosarcoma Oncogenesis.What have we learned about GPER function in physiology and disease from knockout mice?Cancer-related ectopic expression of the bone-related transcription factor RUNX2 in non-osseous metastatic tumor cells is linked to cell proliferation and motilityEffects of chronic estrogen treatment on modulating age-related bone loss in female mice.Gene Expression Profiling in Peripheral Blood Cells and Synovial Membranes of Patients with Psoriatic ArthritisGenomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility.Paternally inherited gsα mutation impairs adipogenesis and potentiates a lean phenotype in vivo.Cell cycle and developmental control of hematopoiesis by Runx1.The molecular mechanisms underlying the pharmacological actions of estrogens, SERMs and oxysterols: implications for the treatment and prevention of osteoporosisThe cancer-related transcription factor Runx2 modulates cell proliferation in human osteosarcoma cell linesLoss of Runx2 sensitises osteosarcoma to chemotherapy-induced apoptosis.MicroRNA functions in osteogenesis and dysfunctions in osteoporosisEstrogenic GPR30 signalling induces proliferation and migration of breast cancer cells through CTGFMicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcoma.The osteogenic transcription factor runx2 controls genes involved in sterol/steroid metabolism, including CYP11A1 in osteoblasts.Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer.PPARgamma2 nuclear receptor controls multiple regulatory pathways of osteoblast differentiation from marrow mesenchymal stem cells.Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1).Isolation and Characterization of Synovial Mesenchymal Stem Cell Derived from Hip Joints: A Comparative Analysis with a Matched Control Knee Group.Genome-wide screening in human growth plates during puberty in one patient suggests a role for RUNX2 in epiphyseal maturation.Role of regulator of G protein signaling proteins in bone.RUNX family: Regulation and diversification of roles through interacting proteins.Novel target genes of RUNX2 transcription factor and 1,25-dihydroxyvitamin D3.Molecular mechanisms of biomaterial-driven osteogenic differentiation in human mesenchymal stromal cells.Runx2 promotes both osteoblastogenesis and novel osteoclastogenic signals in ST2 mesenchymal progenitor cells.Inhibition of Notch1 signaling by Runx2 during osteoblast differentiation.
P2860
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P2860
Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Runx2 regulates G protein-coup ...... wth of osteoblast progenitors.
@en
type
label
Runx2 regulates G protein-coup ...... wth of osteoblast progenitors.
@en
prefLabel
Runx2 regulates G protein-coup ...... wth of osteoblast progenitors.
@en
P2093
P2860
P356
P1476
Runx2 regulates G protein-coup ...... wth of osteoblast progenitors.
@en
P2093
Amjad Javed
Andre J van Wijnen
Daniel W Young
David Lapointe
Gary S Stein
Jane B Lian
Janet L Stein
Jitesh Pratap
Mario Galindo
Nadiya M Teplyuk
P2860
P304
27585-27597
P356
10.1074/JBC.M802453200
P407
P577
2008-07-14T00:00:00Z