Trypanosomatids topoisomerase re-visited. New structural findings and role in drug discovery
about
An Aromatic Diamidine That Targets Kinetoplast DNA, Impairs the Cell Cycle in Trypanosoma cruzi, and Diminishes Trypomastigote Release from Infected Mammalian Host Cells.A lupane-triterpene isolated from Combretum leprosum Mart. fruit extracts that interferes with the intracellular development of Leishmania (L.) amazonensis in vitro.Orientation of DNA Minicircles Balances Density and Topological Complexity in Kinetoplast DNA.From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity.Efficacy of a Binuclear Cyclopalladated Compound Therapy for Cutaneous Leishmaniasis in the Murine Model of Infection with Leishmania amazonensis and Its Inhibitory Effect on Topoisomerase 1B.Nuclear DNA replication and repair in parasites of the genus Leishmania: Exploiting differences to develop innovative therapeutic approaches.
P2860
Trypanosomatids topoisomerase re-visited. New structural findings and role in drug discovery
description
2014 nî lūn-bûn
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2014年の論文
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2014年学术文章
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2014年学术文章
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2014年学术文章
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2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
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2014年學術文章
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2014年學術文章
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name
Trypanosomatids topoisomerase ...... ngs and role in drug discovery
@en
type
label
Trypanosomatids topoisomerase ...... ngs and role in drug discovery
@en
prefLabel
Trypanosomatids topoisomerase ...... ngs and role in drug discovery
@en
P2093
P2860
P50
P1476
Trypanosomatids topoisomerase ...... ngs and role in drug discovery
@en
P2093
Christopher Fernández-Prada
Rafael Balaña-Fouce
Raquel Alvarez-Velilla
P2860
P304
P356
10.1016/J.IJPDDR.2014.07.006
P50
P577
2014-08-24T00:00:00Z