Regulation of T cells by mTOR: the known knowns and the known unknowns.
about
Immunometabolism and the Kinome Peptide Array: A New Perspective and Tool for the Study of Gut HealthTCR signaling to NF-κB and mTORC1: Expanding roles of the CARMA1 complexRapid Quantification of Mitogen-induced Blastogenesis in T Lymphocytes for Identifying Immunomodulatory DrugsT helper 2 (Th2) cell differentiation, type 2 innate lymphoid cell (ILC2) development and regulation of interleukin-4 (IL-4) and IL-13 production.Unstable FoxP3+ T regulatory cells in NZW mice.The autophagy gene Atg16l1 differentially regulates Treg and TH2 cells to control intestinal inflammation.Dual mTOR inhibitor MLN0128 suppresses Merkel cell carcinoma (MCC) xenograft tumor growth.Asymmetric inheritance of mTORC1 kinase activity during division dictates CD8(+) T cell differentiation.Amino acid auxotrophy as a system of immunological control nodes.Modulation of Human Peripheral Blood Mononuclear Cell Signaling by Medicinal Cannabinoids.Roles of Dietary Amino Acids and Their Metabolites in Pathogenesis of Inflammatory Bowel Disease.Amino-acid transporters in T-cell activation and differentiation.Metabolism of murine TH 17 cells: Impact on cell fate and functionperiod-Regulated Feeding Behavior and TOR Signaling Modulate Survival of Infection.An overview of experimental and early investigational therapies for the treatment of polycystic kidney disease.mTOR and its tight regulation for iNKT cell development and effector function.Post-transplantation malignancies: here today, gone tomorrow?Lactic acid in tumor microenvironments causes dysfunction of NKT cells by interfering with mTOR signaling.Suppression of Glut1 and Glucose Metabolism by Decreased Akt/mTORC1 Signaling Drives T Cell Impairment in B Cell Leukemia.Low-dose controlled release of mTOR inhibitors maintains T cell plasticity and promotes central memory T cells.Emerging role of mTOR in the response to cancer therapeutics.Metabolic regulation of inflammation.Immunometabolism in early and late stages of rheumatoid arthritis.Proliferating Helper T Cells Require Rictor/mTORC2 Complex to Integrate Signals from Limiting Environmental Amino Acids.mTORC1 signaling and the metabolic control of cell growth.MenTORing Immunity: mTOR Signaling in the Development and Function of Tissue-Resident Immune Cells.Targeting T cell metabolism to regulate T cell activation, differentiation and function in disease.HIV-1 selectively targets gut-homing CCR6+CD4+ T cells via mTOR-dependent mechanisms.T Cells Encountering Myeloid Cells Programmed for Amino Acid-dependent Immunosuppression Use Rictor/mTORC2 Protein for Proliferative Checkpoint Decisions.Mechanistic Target of Rapamycin Complex 1/S6 Kinase 1 Signals Influence T Cell Activation Independently of Ribosomal Protein S6 PhosphorylationComparative global immune-related gene profiling of somatic cells, human pluripotent stem cells and their derivatives: implication for human lymphocyte proliferation.TUSC2 downregulates PD-L1 expression in non-small cell lung cancer (NSCLC).Type 1 Interferons Potentiate Human CD8+ T-Cell Cytotoxicity Through a STAT4- and Granzyme B-Dependent Pathway.The spectrum of T cell metabolism in health and disease.Features of Effective T Cell-Inducing Vaccines against Chronic Viral Infections.PI3K orchestration of the in vivo persistence of chimeric antigen receptor-modified T cells.Metabolic Reprogramming Commits Differentiation of Human CD27+IgD+ B Cells to Plasmablasts or CD27-IgD- Cells.Biotin Deficiency Induces Th1- and Th17-Mediated Proinflammatory Responses in Human CD4+ T Lymphocytes via Activation of the mTOR Signaling Pathway.The CBM-opathies-A Rapidly Expanding Spectrum of Human Inborn Errors of Immunity Caused by Mutations in the CARD11-BCL10-MALT1 ComplexInhibition of glucose metabolism selectively targets autoreactive follicular helper T cells
P2860
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P2860
Regulation of T cells by mTOR: the known knowns and the known unknowns.
description
2014 nî lūn-bûn
@nan
2014年の論文
@ja
2014年学术文章
@wuu
2014年学术文章
@zh-cn
2014年学术文章
@zh-hans
2014年学术文章
@zh-my
2014年学术文章
@zh-sg
2014年學術文章
@yue
2014年學術文章
@zh
2014年學術文章
@zh-hant
name
Regulation of T cells by mTOR: the known knowns and the known unknowns.
@en
type
label
Regulation of T cells by mTOR: the known knowns and the known unknowns.
@en
prefLabel
Regulation of T cells by mTOR: the known knowns and the known unknowns.
@en
P2860
P356
P1433
P1476
Regulation of T cells by mTOR: the known knowns and the known unknowns.
@en
P2093
Jonathan D Powell
Kristen N Pollizzi
P2860
P356
10.1016/J.IT.2014.11.005
P577
2014-12-16T00:00:00Z