Mechanism and cleavage specificity of the H-N-H endonuclease colicin E9.
about
Mutagenesis identifies the critical amino acid residues of human endonuclease G involved in catalysis, magnesium coordination, and substrate specificityColicin biologyReal-time monitoring of enzymatic DNA hydrolysis by electrospray ionization mass spectrometry.Structural, functional and evolutionary relationships between homing endonucleases and proteins from their host organismsMetal ions and phosphate binding in the H-N-H motif: Crystal structures of the nuclease domain of ColE7/Im7 in complex with a phosphate ion and different divalent metal ionsStructural basis for sequence-dependent DNA cleavage by nonspecific endonucleasesStructure of the complex of the colicin E2 R-domain and its BtuB receptor. The outer membrane colicin transloconElimination of inter-domain interactions increases the cleavage fidelity of the restriction endonuclease DraIIIA new insight into the zinc-dependent DNA-cleavage by the colicin E7 nuclease: a crystallographic and computational studyThe genome sequence of Propionibacterium acidipropionici provides insights into its biotechnological and industrial potentialCofactor requirement of HpyAV restriction endonucleaseFlexibility in the receptor-binding domain of the enzymatic colicin E9 is required for toxicity against Escherichia coli cells.Design of a colicin E7 based chimeric zinc-finger nucleaseFine tuning of the catalytic activity of colicin E7 nuclease domain by systematic N-terminal mutations.Divalent metal ion differentially regulates the sequential nicking reactions of the GIY-YIG homing endonuclease I-BmoI.Programmable RNA recognition and cleavage by CRISPR/Cas9.Structures of the Ultra-High-Affinity Protein-Protein Complexes of Pyocins S2 and AP41 and Their Cognate Immunity Proteins from Pseudomonas aeruginosaCrystal structural analysis and metal-dependent stability and activity studies of the ColE7 endonuclease domain in complex with DNA/Zn2+ or inhibitor/Ni2+Molecular and physiological properties of bacteriophages from North America and Germany affecting the fire blight pathogen Erwinia amylovora.Structural and functional characterization of deep-sea thermophilic bacteriophage GVE2 HNH endonuclease.RecA-dependent programmable endonuclease Ref cleaves DNA in two distinct steps.Nuclease colicins and their immunity proteins.Probing metal ion binding and conformational properties of the colicin E9 endonuclease by electrospray ionization time-of-flight mass spectrometry.Mutagenic scan of the H-N-H motif of colicin E9: implications for the mechanistic enzymology of colicins, homing enzymes and apoptotic endonucleases.Transcriptional profiling of colicin-induced cell death of Escherichia coli MG1655 identifies potential mechanisms by which bacteriocins promote bacterial diversityBiochemical characterization of a thermostable HNH endonuclease from deep-sea thermophilic bacteriophage GVE2.Bacillus subtilis hlpB encodes a conserved stand-alone HNH nuclease-like protein that is essential for viability unless the hlpB deletion is accompanied by the deletion of genes encoding the AddAB DNA repair complex.Tetrameric restriction enzymes: expansion to the GIY-YIG nuclease family.The protein gp74 from the bacteriophage HK97 functions as a HNH endonuclease.Biochemical and mutagenic analysis of I-CreII reveals distinct but important roles for both the H-N-H and GIY-YIG motifsUropathogenic specific protein gene, highly distributed in extraintestinal uropathogenic Escherichia coli, encodes a new member of H-N-H nuclease superfamily.Global structural rearrangement of the cell penetrating ribonuclease colicin E3 on interaction with phospholipid membranes.Distinct conformational stability and functional activity of four highly homologous endonuclease colicins.Rapid detection of colicin E9-induced DNA damage using Escherichia coli cells carrying SOS promoter-lux fusions.Increasing cleavage specificity and activity of restriction endonuclease KpnI.Identification of the catalytic motif of the microbial ribosome inactivating cytotoxin colicin E3.Destabilization of the colicin E9 Endonuclease domain by interaction with negatively charged phospholipids: implications for colicin translocation into bacteria.Structure-based analysis of the metal-dependent mechanism of H-N-H endonucleases.Insights from the complete genome sequence of Clostridium tyrobutyricum provide a platform for biotechnological and industrial applications.Structural insights into the mechanism of nuclease A, a betabeta alpha metal nuclease from Anabaena.
P2860
Q21284426-63508F81-8C13-4C6C-AF0D-0D5CB13717F0Q24671701-7DB0F54B-4BAF-4226-AE43-82D4C6C4B620Q24810397-1D8ABC31-07F2-4CBA-9FE9-F9F084FE5375Q26865226-133DF3C6-5CF3-44DE-B9B4-F1155AF729C7Q27639991-60048580-7E5B-4E7A-BC9E-B399EF24B92CQ27640818-0CBE840A-A7F6-412C-B900-41FEB4F757D9Q27645252-E0490B27-100B-4D65-89FB-10643B3C41CEQ27683352-B6F7436A-D830-4830-BA49-E754DD53AA39Q27694911-3B6FFECA-A11A-4D70-8941-379F6C8DAF31Q28710130-7A7C0034-956A-4D9E-8368-045E2A8F6944Q28749088-1F05578A-9359-4C49-8297-8C5ECE111047Q31087102-380769E5-A738-4993-AD77-5D21B45161BEQ33922101-371764BA-6848-4349-91FA-05577E63F3A8Q33977832-6B8ABD15-6B7E-43AD-ACB9-E7F5B8098359Q34009602-6D9DB396-CE9E-4AE3-B0DC-BF5D11F07978Q34042210-66A1250D-B07C-43BF-968C-F89D330F56CFQ35717256-254E867A-4F5C-471E-8050-F7239E4927D0Q36458227-6DA8A9B8-E25C-477E-B947-6443C844FA43Q37273559-07BE68DD-3394-475B-84A2-6E2E217FBBFBQ37638040-C82ECE15-CF21-4B3E-BEDE-1B3E7C901A39Q37680429-E2060180-1D0E-4EB5-9681-EF5273FF14D0Q37956420-41C2F5DE-A0B8-46EB-8FE0-ED87DB146F0CQ38270005-0C477E87-BAEF-4AB1-9EDE-C297B600201BQ39681869-82E7A1E9-060D-49F4-9997-14493D8B3F6FQ40469231-E413A266-1A07-4527-8715-AB4716A64489Q40774728-26662E70-39CB-4585-A43E-393D865929B9Q41577128-DD455087-E3E5-42BA-A081-6E24477188B5Q41820271-5C06D438-28B9-4B55-8428-5D0771DC2988Q41845016-4A557072-8EF4-45D1-844A-B631D8E7A2CAQ42114363-D187BFF2-7C7D-4D15-9EFE-A07518FEC455Q42161973-E27A23E6-5D00-4896-BF15-4A696CCE3558Q42264439-BCBD3D0A-3A62-46CF-A072-B56F842BE16CQ42282312-2632C5A6-ED18-4593-8DCB-2DBE823E5ED9Q42604367-8A497A0B-F3BC-44C7-9AB5-C4F4DBBE3075Q42876257-D59EAB2A-C4B0-4319-B0CA-D6166A48C189Q43095080-7CF73CEC-C4CA-4956-BE1E-EB93868D823BQ44814642-62CFDB45-0110-45C0-AF72-E77ECB089C66Q44931288-11C8F6A7-66E9-4CA1-B56A-B9036792CBDEQ46361707-8E068BC2-6653-4020-9377-8EE964483D90Q46493466-32EDF1AB-636D-4BFC-B029-9F7E07958D0E
P2860
Mechanism and cleavage specificity of the H-N-H endonuclease colicin E9.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
Mechanism and cleavage specificity of the H-N-H endonuclease colicin E9.
@en
type
label
Mechanism and cleavage specificity of the H-N-H endonuclease colicin E9.
@en
prefLabel
Mechanism and cleavage specificity of the H-N-H endonuclease colicin E9.
@en
P2093
P356
P1476
Mechanism and cleavage specificity of the H-N-H endonuclease colicin E9.
@en
P2093
A H Keeble
A J Pommer
A M Hemmings
B A Connolly
C Kleanthous
P304
P356
10.1006/JMBI.2001.5189
P407
P50
P577
2001-12-01T00:00:00Z