The Phe-X-Glu DNA binding motif of MutS. The role of hydrogen bonding in mismatch recognition.
about
DNA mismatch repair: molecular mechanism, cancer, and ageingCorrecting errors in synthetic DNA through consensus shuffling.Determination of protein-DNA binding constants and specificities from statistical analyses of single molecules: MutS-DNA interactions8-oxoguanine incorporation into DNA repeats in vitro and mismatch recognition by MutSalpha.Structures of Escherichia coli DNA mismatch repair enzyme MutS in complex with different mismatches: a common recognition mode for diverse substratesMagnesium Coordination Controls the Molecular Switch Function of DNA Mismatch Repair Protein MutSDNA mismatch repair in eukaryotes and bacteriaMechanism of MutS searching for DNA mismatches and signaling repairChemical trapping of the dynamic MutS-MutL complex formed in DNA mismatch repair in Escherichia coli.Evolutionary Covariance Combined with Molecular Dynamics Predicts a Framework for Allostery in the MutS DNA Mismatch Repair Protein.Saccharomyces cerevisiae Msh2-Msh6 DNA binding kinetics reveal a mechanism of targeting sites for DNA mismatch repair.Biological properties of single chemical-DNA adducts: a twenty year perspectiveDNA scissors device used to measure MutS binding to DNA mis-pairsDNA binding properties of the yeast Msh2-Msh6 and Mlh1-Pms1 heterodimers.High-fidelity in vivo replication of DNA base shape mimics without Watson-Crick hydrogen bonds.Specialized mismatch repair function of Glu339 in the Phe-X-Glu motif of yeast Msh6Chimeric Saccharomyces cerevisiae Msh6 protein with an Msh3 mispair-binding domain combines properties of both proteins.Deciphering the mismatch recognition cycle in MutS and MSH2-MSH6 using normal-mode analysis.Chromosomal directionality of DNA mismatch repair in Escherichia coliLong-Range Signaling in MutS and MSH Homologs via Switching of Dynamic Communication PathwaysHuman DNA mismatch repair: coupling of mismatch recognition to strand-specific excisionThe difluorotoluene debate--a decade later.Structure and mechanism for DNA lesion recognition.Sequence context effect for hMSH2-hMSH6 mismatch-dependent activation.Evidence that msh1p plays multiple roles in mitochondrial base excision repair.DNA base repair--recognition and initiation of catalysis.Recognition of damaged DNA: structure and dynamic markers.Mismatch binding, ADP-ATP exchange and intramolecular signaling during mismatch repair.Multiple factors insulate Msh2-Msh6 mismatch repair activity from defects in Msh2 domain I.Dominant Saccharomyces cerevisiae msh6 mutations cause increased mispair binding and decreased dissociation from mispairs by Msh2-Msh6 in the presence of ATP.Asymmetric recognition of DNA local distortion. Structure-based functional studies of eukaryotic Msh2-Msh6.Dual role of MutS glutamate 38 in DNA mismatch discrimination and in the authorization of repair.Dynamics of MutS-mismatched DNA complexes are predictive of their repair phenotypesSingle-molecule FRET TACKLE reveals highly dynamic mismatched DNA-MutS complexes.Impact of mutS inactivation on foreign DNA acquisition by natural transformation in Pseudomonas stutzeri.The effects of nucleotides on MutS-DNA binding kinetics clarify the role of MutS ATPase activity in mismatch repair.The role of nucleotide cofactor binding in cooperativity and specificity of MutS recognition.The molecular mechanism of DNA damage recognition by MutS homologs and its consequences for cell death responseSlow conformational changes in MutS and DNA direct ordered transitions between mismatch search, recognition and signaling of DNA repair.DnaN clamp zones provide a platform for spatiotemporal coupling of mismatch detection to DNA replication.
P2860
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P2860
The Phe-X-Glu DNA binding motif of MutS. The role of hydrogen bonding in mismatch recognition.
description
2001 nî lūn-bûn
@nan
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
2001年论文
@zh
2001年论文
@zh-cn
name
The Phe-X-Glu DNA binding moti ...... nding in mismatch recognition.
@en
type
label
The Phe-X-Glu DNA binding moti ...... nding in mismatch recognition.
@en
prefLabel
The Phe-X-Glu DNA binding moti ...... nding in mismatch recognition.
@en
P2093
P2860
P356
P1476
The Phe-X-Glu DNA binding moti ...... nding in mismatch recognition.
@en
P2093
P2860
P304
45505-45508
P356
10.1074/JBC.C100449200
P407
P577
2001-10-15T00:00:00Z