Suppression of eosinophil function by RP 73401, a potent and selective inhibitor of cyclic AMP-specific phosphodiesterase: comparison with rolipram.
about
Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3Bronchodilator and anti-inflammatory activities of glaucine: In vitro studies in human airway smooth muscle and polymorphonuclear leukocytesPotential role of phosphodiesterase 7 in human T cell function: comparative effects of two phosphodiesterase inhibitorsDesign of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safetyEffects of PDE4 inhibitors on lipopolysaccharide-induced priming of superoxide anion production from human mononuclear cellsModulation of eotaxin formation and eosinophil migration by selective inhibitors of phosphodiesterase type 4 isoenzymeThe effect of selective phosphodiesterase 3 and 4 isoenzyme inhibitors and established anti-asthma drugs on inflammatory cell activationEvidence that cyclic AMP phosphodiesterase inhibitors suppress interleukin-2 release from murine splenocytes by interacting with a 'low-affinity' phosphodiesterase 4 conformer.Effects of phosphodiesterase inhibitors on human lung mast cell and basophil function.Phosphodiesterase profile of human B lymphocytes from normal and atopic donors and the effects of PDE inhibition on B cell proliferation.The effects of phosphodiesterase type 4 inhibitors on tumour necrosis factor-alpha and leukotriene B4 in a novel human whole blood assay.The inhibition of antigen-induced eosinophilia and bronchoconstriction by CDP840, a novel stereo-selective inhibitor of phosphodiesterase type 4.Effects of agents which elevate cyclic AMP on guinea-pig eosinophil homotypic aggregationCDP840: a novel inhibitor of PDE-4.Characterization of CHO-K1 cells stably expressing PDE-IV enzymes. Whole-cell cAMP determinations vs broken-cell enzymatic assays.Anti-inflammatory effects of theophylline and selective phosphodiesterase inhibitors.Phosphodiesterase isozymes: molecular targets for novel antiasthma agents.Evidence that cyclic AMP phosphodiesterase inhibitors suppress TNF alpha generation from human monocytes by interacting with a 'low-affinity' phosphodiesterase 4 conformer.Effects of inhibitors of phosphodiesterase, on antigen-induced bronchial hyperreactivity in conscious sensitized guinea-pigs and airway leukocyte infiltration.Inhibition of eotaxin-mediated human eosinophil activation and migration by the selective cyclic nucleotide phosphodiesterase type 4 inhibitor rolipram.Effects of rolipram on cyclic AMP levels in alveolar macrophages and lipopolysaccharide-induced inflammation in mouse lung.Correlations of PDE-4 inhibition between enzymes of smooth muscle and inflammatory cell sources.Signal transduction and activation of the NADPH oxidase in eosinophils.
P2860
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P2860
Suppression of eosinophil function by RP 73401, a potent and selective inhibitor of cyclic AMP-specific phosphodiesterase: comparison with rolipram.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Suppression of eosinophil func ...... ase: comparison with rolipram.
@en
type
label
Suppression of eosinophil func ...... ase: comparison with rolipram.
@en
prefLabel
Suppression of eosinophil func ...... ase: comparison with rolipram.
@en
P2093
P2860
P1476
Suppression of eosinophil func ...... ase: comparison with rolipram.
@en
P2093
Karlsson JA
Palfreyman MN
Souness JE
P2860
P356
10.1111/J.1476-5381.1995.TB16317.X
P407
P577
1995-05-01T00:00:00Z