The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance. - Wikidata - wikimedia - TriplyDB

The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance.

The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance.

http://www.wikidata.org/entity/Q38298765

about

Targeted approaches to induce immune tolerance for Pompe disease therapy Novel Findings into AIRE Genetics and Functioning: Clinical Implications Cellular and molecular regulation of innate inflammatory responses Autoimmunity in 2015.Reversible modulation of SIRT1 activity in a mouse strain.Central tolerance to self revealed by the autoimmune regulator.Targeting Sirtuin-1 prolongs murine renal allograft survival and function.Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy.AIRE: From promiscuous molecular partnerships to promiscuous gene expression.AIRE expands: new roles in immune tolerance and beyond.Autoimmune regulator and self-tolerance - molecular and clinical aspects.Seeding for sirtuins: microseed matrix seeding to obtain crystals of human Sirt3 and Sirt2 suitable for soaking.Extensive RNA editing and splicing increase immune self-representation diversity in medullary thymic epithelial cells.FBXO3 Protein Promotes Ubiquitylation and Transcriptional Activity of AIRE (Autoimmune Regulator)Ectopic Aire Expression in the Thymic Cortex Reveals Inherent Properties of Aire as a Tolerogenic Factor within the Medulla.Recruitment by the Repressor Freud-1 of Histone Deacetylase-Brg1 Chromatin Remodeling Complexes to Strengthen HTR1A Gene Repression.Insights into immune tolerance from AIRE deficiency.Quantitative analysis of protein-protein interactions and post-translational modifications in rare immune populations.Update on Aire and thymic negative selection.Aire controls the recirculation of murine Foxp3+ regulatory T-cells back to the thymus.The molecular basis of immune regulation in autoimmunity.Twenty Years of AIRE.Switching on the Aire conditioner.HDAC3 Is a Master Regulator of mTEC Development.Mitochondrial Deacetylase SIRT3 Plays an Important Role in Donor T Cell Responses after Experimental Allogeneic Hematopoietic Transplantation SIRT1 activation attenuates α cell hyperplasia, hyperglucagonaemia and hyperglycaemia in STZ-diabetic mice Epigenetic Regulation of Autophagy: A Path to the Control of Autoimmunity

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The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance.

http://www.wikidata.org/entity/Q38298765

description

2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

@zh-tw

2015年论文

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2015年论文

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2015年论文

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name

The deacetylase Sirt1 is an es ...... ntral immunological tolerance.

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type

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The deacetylase Sirt1 is an es ...... ntral immunological tolerance.

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The deacetylase Sirt1 is an es ...... ntral immunological tolerance.

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Nature Immunology

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The deacetylase Sirt1 is an es ...... ntral immunological tolerance.

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Adi Jacob

http://www.w3.org/2001/XMLSchema#string

Anna Chuprin

http://www.w3.org/2001/XMLSchema#string

Asaf Sela

http://www.w3.org/2001/XMLSchema#string

Ayelet Avin

http://www.w3.org/2001/XMLSchema#string

Ben Levi

http://www.w3.org/2001/XMLSchema#string

Clotilde Guyon

http://www.w3.org/2001/XMLSchema#string

Eystein S Husebye

http://www.w3.org/2001/XMLSchema#string

Haim Y Cohen

http://www.w3.org/2001/XMLSchema#string

Irit Sagi

http://www.w3.org/2001/XMLSchema#string

Jakub Abramson

http://www.w3.org/2001/XMLSchema#string

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Aire's partners in the molecular control of immunological tolerance

The autoimmune regulator PHD finger binds to non-methylated histone H3K4 to activate gene expression

The mammalian SIR2alpha protein has a role in embryogenesis and gametogenesis

Transcriptional regulation by AIRE: molecular mechanisms of central tolerance

Deletional tolerance mediated by extrathymic Aire-expressing cells

Positional cloning of the APECED gene

Characterization of a human gene with sequence homology to Saccharomyces cerevisiae SIR2

Aire deficient mice develop multiple features of APECED phenotype and show altered immune response

Projection of an immunological self shadow within the thymus by the aire protein

Positive and negative selection of the T cell repertoire: what thymocytes see (and don't see)

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737-745

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scholarly article

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10.1038/NI.3194

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7

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16

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Matthieu Giraud

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2015-05-25T00:00:00Z

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26006015

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