Glycosaminoglycans facilitate procathepsin B activation through disruption of propeptide-mature enzyme interactions.
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Cysteine Proteases: Modes of Activation and Future Prospects as Pharmacological TargetsProtease signalling: the cutting edgeOptimizing dentin bond durability: control of collagen degradation by matrix metalloproteinases and cysteine cathepsinsCathepsin X is secreted by human osteoblasts, digests CXCL-12 and impairs adhesion of hematopoietic stem and progenitor cells to osteoblastsHeparinoids activate a protease, secreted by mucosa and tumors, via tethering supplemented by allostery.Infection of XC cells by MLVs and Ebola virus is endosome-dependent but acidification-independent.Heparin modulates the endopeptidase activity of Leishmania mexicana cysteine protease cathepsin L-Like rCPB2.8.Cysteine Cathepsins Activate ELR Chemokines and Inactivate Non-ELR Chemokines.Autocatalytic processing of procathepsin B is triggered by proenzyme activityModulatory effects of proteoglycans on proteinase activities.Evaluation of serum procathepsin B, cystatin B and cystatin C as possible biomarkers of ovarian cancerLive-cell imaging demonstrates extracellular matrix degradation in association with active cathepsin B in caveolae of endothelial cells during tube formation.Cell-matrix interactions: focus on proteoglycan-proteinase interplay and pharmacological targeting in cancer.The role of NH4Cl and cysteine proteases in Human Papillomavirus type 16 infection.Acid-mediated tumor proteolysis: contribution of cysteine cathepsinsProteolytic networks in cancerCathepsins in digestive cancers.HIV Protease Inhibitor-Induced Cathepsin Modulation Alters Antigen Processing and Cross-PresentationCathepsin B: Basis Sequence: Mouse.Chondroitin sulfate promotes activation of cathepsin K.Cysteine cathepsin activity regulation by glycosaminoglycans.ADP-ribosylation factor 1 protein regulates trypsinogen activation via organellar trafficking of procathepsin B protein and autophagic maturation in acute pancreatitis.Inhibition of gingipains by their profragments as the mechanism protecting Porphyromonas gingivalis against premature activation of secreted proteases.Conformational flexibility and allosteric regulation of cathepsin K.Expression and activity profiling of selected cysteine cathepsins and matrix metalloproteinases in synovial fluids from patients with rheumatoid arthritis and osteoarthritis.The Multifaceted Role of the Lysosomal Protease Cathepsins in Kidney Disease.Activation of cathepsin D by glycosaminoglycans.Insights on a new path of pre-mitochondrial apoptosis regulation by a glycosaminoglycan mimetic.Live Cell Imaging and Profiling of Cysteine Cathepsin Activity Using a Quenched Activity-Based Probe.
P2860
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P2860
Glycosaminoglycans facilitate procathepsin B activation through disruption of propeptide-mature enzyme interactions.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Glycosaminoglycans facilitate ...... de-mature enzyme interactions.
@en
type
label
Glycosaminoglycans facilitate ...... de-mature enzyme interactions.
@en
prefLabel
Glycosaminoglycans facilitate ...... de-mature enzyme interactions.
@en
P2093
P2860
P356
P1476
Glycosaminoglycans facilitate ...... de-mature enzyme interactions.
@en
P2093
Boris Turk
Dejan Caglic
Gunnar Pejler
Jerica Rozman Pungercar
P2860
P304
33076-33085
P356
10.1074/JBC.M705761200
P407
P577
2007-08-28T00:00:00Z