EWS/FLI1 regulates tumor angiogenesis in Ewing's sarcoma via suppression of thrombospondins.
about
The oncogenic EWS-FLI1 protein binds in vivo GGAA microsatellite sequences with potential transcriptional activation functionGLI1 is a central mediator of EWS/FLI1 signaling in Ewing tumors.Angiogenesis and vascular targeting in Ewing sarcoma: a review of preclinical and clinical data.ABT-869 inhibits the proliferation of Ewing Sarcoma cells and suppresses platelet-derived growth factor receptor beta and c-KIT signaling pathways.Is There a Predisposition Gene for Ewing's Sarcoma?Dual targeting of EWS-FLI1 activity and the associated DNA damage response with trabectedin and SN38 synergistically inhibits Ewing sarcoma cell growthThe miR-17-92 cluster and its target THBS1 are differentially expressed in angiosarcomas dependent on MYC amplificationCopy Number Alterations and Methylation in Ewing's Sarcoma.Oncogenic fusion protein EWS/FLI1 down-regulates gene expression by both transcriptional and posttranscriptional mechanismsTargeted therapy in pediatric and adolescent oncology.Genetically defined EWS/FLI1 model system suggests mesenchymal origin of Ewing's family tumors.HIF-1α represses the expression of the angiogenesis inhibitor thrombospondin-2.USP6 activation in nodular fasciitis by promoter-swapping gene fusions.
P2860
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P2860
EWS/FLI1 regulates tumor angiogenesis in Ewing's sarcoma via suppression of thrombospondins.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
EWS/FLI1 regulates tumor angio ...... uppression of thrombospondins.
@en
type
label
EWS/FLI1 regulates tumor angio ...... uppression of thrombospondins.
@en
prefLabel
EWS/FLI1 regulates tumor angio ...... uppression of thrombospondins.
@en
P2093
P1433
P1476
EWS/FLI1 regulates tumor angio ...... uppression of thrombospondins.
@en
P2093
Christopher T Denny
Eugenie S Kleinerman
Gary Potikyan
Julie M Gaulden
Kelly A France
Rupert O V Savene
Stephen L Lessnick
Zhichao Zhou
P304
P356
10.1158/0008-5472.CAN-06-4140
P407
P577
2007-07-01T00:00:00Z