G-protein antisense oligodeoxyribonucleotides and mu-opioid supraspinal antinociception.
about
Crystal structure of the µ-opioid receptor bound to a morphinan antagonistDifferential prevention of morphine amnesia by antisense oligodeoxynucleotides directed against various Gi-protein alpha subunitsNonselective coupling of the human mu-opioid receptor to multiple inhibitory G-protein isoformsDifferential modulation of mu-opioid receptor signaling to adenylyl cyclase by regulators of G protein signaling proteins 4 or 8 and 7 in permeabilised C6 cells is Galpha subtype dependent.3-Methoxynaltrexone, a selective heroin/morphine-6beta-glucuronide antagonist.Subgroups among mu-opioid receptor agonists distinguished by ATP-sensitive K+ channel-acting drugs.μ-Opioid receptor coupling to Gα(o) plays an important role in opioid antinociception.A potential novel strategy to separate therapeutic- and side-effects that are mediated via the same receptor: beta-arrestin2/G-protein coupling antagonists.Ligand-biased activation of extracellular signal-regulated kinase 1/2 leads to differences in opioid induced antinociception and tolerance.Identification of an additional supraspinal component to the analgesic mechanism of action of buprenorphine.RGSZ1 and GAIP regulate mu- but not delta-opioid receptors in mouse CNS: role in tachyphylaxis and acute tolerance.Gx/z is regulated by mu but not delta opioid receptors in the stimulation of the low Km GTPase activity in mouse periaqueductal grey matter.Agonists activate Gi1 alpha or Gi2 alpha fused to the human mu opioid receptor differently.Identification of a Conformational Equilibrium That Determines the Efficacy and Functional Selectivity of the μ-Opioid Receptor.Hypofunctionality of Gi proteins as aetiopathogenic mechanism for migraine and cluster headache.Influence of Gz and Gi2 transducer proteins in the affinity of opioid agonists to mu receptors.
P2860
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P2860
G-protein antisense oligodeoxyribonucleotides and mu-opioid supraspinal antinociception.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
G-protein antisense oligodeoxyribonucleotides and mu-opioid supraspinal antinociception.
@en
type
label
G-protein antisense oligodeoxyribonucleotides and mu-opioid supraspinal antinociception.
@en
prefLabel
G-protein antisense oligodeoxyribonucleotides and mu-opioid supraspinal antinociception.
@en
P2093
P1476
G-protein antisense oligodeoxyribonucleotides and mu-opioid supraspinal antinociception.
@en
P2093
Connelly CD
Martinez RP
P356
10.1016/0014-2999(94)90073-6
P407
P577
1994-06-01T00:00:00Z