Epirubicin upregulates UDP glucuronosyltransferase 2B7 expression in liver cancer cells via the p53 pathway.

Epirubicin upregulates UDP glucuronosyltransferase 2B7 expression in liver cancer cells via the p53 pathway.

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http://www.wikidata.org/entity/Q38308097
Drug-Metabolizing Activity, Protein and Gene Expression of UDP-Glucuronosyltransferases Are Significantly Altered in Hepatocellular Carcinoma PatientsBrain-derived neurotrophic factor involved epigenetic repression of UGT2B7 in colorectal carcinoma: A mechanism to alter morphine glucuronidation in tumor.Reduction of p53 by knockdown of the UGT1 locus in colon epithelial cells causes an increase in tumorigenesis.Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism.Metabolic activation of 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine and DNA adduct formation depends on p53: Studies in Trp53(+/+),Trp53(+/-) and Trp53(-/-) miceTranscriptional regulation of human UDP-glucuronosyltransferase genes.Significantly decreased and more variable expression of major CYPs and UGTs in liver microsomes prepared from HBV-positive human hepatocellular carcinoma and matched pericarcinomatous tissues determined using an isotope label-free UPLC-MS/MS method.
P2860

Epirubicin upregulates UDP glucuronosyltransferase 2B7 expression in liver cancer cells via the p53 pathway.

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http://www.wikidata.org/entity/Q38308097
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2014 nî lūn-bûn
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Epirubicin upregulates UDP glu ...... cer cells via the p53 pathway.
@en
type
label
Epirubicin upregulates UDP glu ...... cer cells via the p53 pathway.
@en
prefLabel
Epirubicin upregulates UDP glu ...... cer cells via the p53 pathway.
@en
P1433
P1476
P2093
P304
P31
P356
P433
P478
P50
P577
P5875
P698
P356
P1433
P1476
Epirubicin upregulates UDP glu ...... ncer cells via the p53 pathway
@en
P2093
P304
P31
P356
P433
P478
P50
P577
P5875
P698