The identification of a volume-regulated anion channel: an amazing Odyssey.
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LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic StrengthDistinct contributions of LRRC8A and its paralogs to the VSOR anion channel from those of the ASOR anion channel.Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs.Volume-regulated anion channel--a frenemy within the brain.Leucine-rich repeat containing protein LRRC8A is essential for swelling-activated Cl- currents and embryonic development in zebrafishSpecific and essential but not sufficient roles of LRRC8A in the activity of volume-sensitive outwardly rectifying anion channel (VSOR)Inhibition of Regulatory Volume Decrease Enhances the Cytocidal Effect of Hypotonic Shock in Hepatocellular Carcinoma.Intracellular levels of glutamate in swollen astrocytes are preserved via neurotransmitter reuptake and de novo synthesis: implications for hyponatremia.LRRC8A channels support TNFα-induced superoxide production by Nox1 which is required for receptor endocytosis.MLC1 protein: a likely link between leukodystrophies and brain channelopathies.VRAC: molecular identification as LRRC8 heteromers with differential functions.Role of volume-regulated and calcium-activated anion channels in cell volume homeostasis, cancer and drug resistanceBiophysics and Physiology of the Volume-Regulated Anion Channel (VRAC)/Volume-Sensitive Outwardly Rectifying Anion Channel (VSOR).Inactivation and Anion Selectivity of Volume-regulated Anion Channels (VRACs) Depend on C-terminal Residues of the First Extracellular Loop.Ion channels in regulated cell death.Chloride Dysregulation, Seizures, and Cerebral Edema: A Relationship with Therapeutic Potential.The role of stretch-activated ion channels in acute respiratory distress syndrome: finally a new target?Cl- channels in apoptosis.ATP release during cell swelling activates a Ca2+-dependent Cl- current by autocrine mechanism in mouse hippocampal microglia.The calcium-activated potassium channel KCa3.1 plays a central role in the chemotactic response of mammalian neutrophils.Investigation of LRRC8-Mediated Volume-Regulated Anion Currents in Xenopus Oocytes.VRACs swallow platinum drugs.The combined activation of KCa3.1 and inhibition of Kv11.1/hERG1 currents contribute to overcome Cisplatin resistance in colorectal cancer cells.When size matters: transient receptor potential vanilloid 4 channel as a volume-sensor rather than an osmo-sensor.Can we make physiological research better?Leucine-rich repeat containing 8A (LRRC8A)-dependent volume-regulated anion channel activity is dispensable for T-cell development and function.The role of TRPM2 channels in neurons, glial cells and the blood-brain barrier in cerebral ischemia and hypoxia.Borders and beyond.Channels and channelopathies.Sex sells,…..Characterization of Human Dermal Fibroblasts in Fabry Disease.LRRC8/VRAC anion channels enhance β-cell glucose sensing and insulin secretion.Expression of LRRC8/VRAC Currents in Xenopus Oocytes: Advantages and Caveats.ATP Release Channels.LRRC8 N termini influence pore properties and gating of volume-regulated anion channels (VRACs)Deficient LRRC8A-dependent volume-regulated anion channel activity is associated with male infertility in mice
P2860
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P2860
The identification of a volume-regulated anion channel: an amazing Odyssey.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
The identification of a volume-regulated anion channel: an amazing Odyssey.
@en
type
label
The identification of a volume-regulated anion channel: an amazing Odyssey.
@en
prefLabel
The identification of a volume-regulated anion channel: an amazing Odyssey.
@en
P2860
P356
P1433
P1476
The identification of a volume-regulated anion channel: an amazing Odyssey.
@en
P2093
P2860
P304
P356
10.1111/APHA.12450
P577
2015-01-28T00:00:00Z