The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation.
about
The human 20-kDa 5'-(CGG)(n)-3'-binding protein is targeted to the nucleus and affects the activity of the FMR1 promoterA highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2POn the aggregation properties of FMRP--a link with the FXTAS syndrome?The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2FXR1, an autosomal homolog of the fragile X mental retardation geneA close relative of the adrenoleukodystrophy (ALD) gene codes for a peroxisomal protein with a specific expression patternFragile x syndromeSpecific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among themA pilot open label, single dose trial of fenobam in adults with fragile X syndrome.Abnormal dendritic spines in fragile X knockout mice: maturation and pruning deficitsFragile X mental retardation protein is translated near synapses in response to neurotransmitter activationMuscle specific fragile X related protein 1 isoforms are sequestered in the nucleus of undifferentiated myoblastRNA Secondary Structure Modulates FMRP's Bi-Functional Role in the MicroRNA PathwayMouse Genetic Models of Human Brain DisordersSingle-Nucleotide Mutations in FMR1 Reveal Novel Functions and Regulatory Mechanisms of the Fragile X Syndrome Protein FMRPDevelopment and plasticity of the Drosophila larval neuromuscular junctionFragile X spectrum disordersEmerging pharmacologic treatment options for fragile X syndromeUnstable mutations in the FMR1 gene and the phenotypesThe pathophysiology of fragile X (and what it teaches us about synapses)The unstable repeats--three evolving faces of neurological diseaseTracking the Fragile X Mental Retardation Protein in a Highly Ordered Neuronal RiboNucleoParticles Population: A Link between Stalled Polyribosomes and RNA GranulesStructural Studies of the Tandem Tudor Domains of Fragile X Mental Retardation Related Proteins FXR1 and FXR2Detection and Quantification of the Fragile X Mental Retardation Protein 1 (FMRP)G-quadruplexes: Emerging roles in neurodegenerative diseases and the non-coding transcriptomeNuclear Fragile X Mental Retardation Protein is localized to Cajal bodiesFragile X mental retardation protein stimulates ribonucleoprotein assembly of influenza A virusDicer-derived microRNAs are utilized by the fragile X mental retardation protein for assembly on target RNAsIn vitro and in cellulo evidences for association of the survival of motor neuron complex with the fragile X mental retardation proteinMOV10 and FMRP regulate AGO2 association with microRNA recognition elementsTranslational regulation of the human achaete-scute homologue-1 by fragile X mental retardation proteinFragile X mental retardation protein FMRP binds mRNAs in the nucleusDifferent targets for the fragile X-related proteins revealed by their distinct nuclear localizationsThe fragile X gene and its functionIdentification of mRNA/protein (mRNP) complexes containing Puralpha, mStaufen, fragile X protein, and myosin Va and their association with rough endoplasmic reticulum equipped with a kinesin motorFrataxin is reduced in Friedreich ataxia patients and is associated with mitochondrial membranesRNA and microRNAs in fragile X mental retardationThe fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif.The Epac1 signaling pathway regulates Cl- secretion via modulation of apical KCNN4c channels in diarrheaFMR1 transcript isoforms: association with polyribosomes; regional and developmental expression in mouse brain
P2860
Q22253241-D72AA4ED-4E9B-4AE3-BADF-C658798D8160Q24291408-6D19A298-C95B-4D1D-8C24-133CAED2CA07Q24298281-6A5D99D9-9105-4390-9427-F92F1726BAE6Q24303859-5C4DABE1-EA0A-4F51-B92A-5367ACBDE92BQ24321996-8651C349-CE96-467D-8257-4007C8CA0842Q24567552-3932C161-29F8-4D35-9561-E8D3A97427B5Q24633000-AD1260A5-1530-4FA5-AA01-6501CD3B7C57Q24648900-0C5A1F1F-6D89-4580-889A-BCF1647C581BQ24654933-11BDFC32-134F-4B27-B815-EA023EDD1AB7Q24657867-59197F1E-A16C-467B-AF53-B51C5505F69AQ24657890-8C0BF49F-9B3A-429C-8BC3-7F8F1344CA03Q24795709-A6DF18EB-C5EC-4B60-8258-0EFEF319B68AQ26747489-76A5A99A-32F6-4345-9CD9-C88ED1663FC1Q26752246-AA4AA96C-E3A0-42A1-92C3-A6B670B96C50Q26773167-B6B23724-1FD4-41AA-8570-44BCCCDA17EEQ26820443-A7E3BE33-7A5B-4AAB-BB27-1BF1499B3991Q26824376-B491CE50-8E4A-45C4-967E-0D3E13A29594Q26829152-EF02EAED-1BA6-4D3C-885F-F90B096C7903Q26996649-492F1D1B-41B6-4064-9034-A8C29D2C1D46Q27010675-0834290A-0636-4B7F-8F17-96B03FB9AA18Q27025923-04D74725-15D4-4EDA-B049-CEE09A642D2DQ27308310-8CA34BA6-A13A-43A4-B5D9-3CDC3859D60AQ27665857-CB648B5B-1C21-40CB-BB50-1F7029277F14Q28079967-6E34D3A1-B99F-4787-8A36-5038751ECEE7Q28084249-25BDB647-BA28-41E6-AA72-7D41766BBF94Q28115047-165D4783-8AD6-4747-A0FC-79D96BBE0B77Q28115134-F6B4B042-DE2E-43F1-AACA-7479B797B0D4Q28115922-70C9AD38-5FB4-425A-A682-369FC7D800C3Q28116617-C1555A40-C6F9-4C3B-96B0-2CD9A43CD7B0Q28117661-1DCF2B0B-5DF8-4842-8B83-A7F422E9ACFFQ28119013-756A7D7B-1472-4448-A566-C20714E663DEQ28119156-EC342B58-E2C5-40F2-A3CB-E90B5B6EF904Q28141005-247CCD9A-6257-4681-A2BC-47BE514C0E1AQ28201533-A55A740D-6769-4B7C-B69A-DB7619995DC2Q28216333-147C2621-944F-46EE-BAED-4BAC8CA3987FQ28249379-E1D8B6C2-764A-4988-8C26-408A27B7E950Q28290772-660CF8B4-DA32-4AFB-8601-BA1FE54C0E0EQ28348391-6434F139-9ECE-4FE3-A46F-D5967E8FDC90Q28385670-9696E901-5C67-48AF-96F1-111A77B37AA0Q28487767-EDF68E70-67CC-4530-AC18-5075F884F243
P2860
The FMR-1 protein is cytoplasmic, most abundant in neurons and appears normal in carriers of a fragile X premutation.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
The FMR-1 protein is cytoplasm ...... rs of a fragile X premutation.
@en
type
label
The FMR-1 protein is cytoplasm ...... rs of a fragile X premutation.
@en
prefLabel
The FMR-1 protein is cytoplasm ...... rs of a fragile X premutation.
@en
P2093
P2860
P356
P1433
P1476
The FMR-1 protein is cytoplasm ...... rs of a fragile X premutation.
@en
P2093
P2860
P2888
P304
P356
10.1038/NG0893-335
P407
P577
1993-08-01T00:00:00Z