Identification and characterization of a ligand-independent oligomerization domain in the extracellular region of the CD95 death receptor.
about
Palmitoylation of CD95 facilitates formation of SDS-stable receptor aggregates that initiate apoptosis signalingPrinciples of antibody-mediated TNF receptor activationPrecise mapping of the CD95 pre-ligand assembly domain.In vivo UVB irradiation induces clustering of Fas (CD95) on human epidermal cells.Synthetic constrained peptide selectively binds and antagonizes death receptor 5.An essential role for membrane rafts in the initiation of Fas/CD95-triggered cell death in mouse thymocytesThe pre-ligand binding assembly domain: a potential target of inhibition of tumour necrosis factor receptor function.Intra- and interdimeric caspase-8 self-cleavage controls strength and timing of CD95-induced apoptosis.p53-mediated delayed NF-κB activity enhances etoposide-induced cell death in medulloblastoma.The receptor kinases LePRK1 and LePRK2 associate in pollen and when expressed in yeast, but dissociate in the presence of style extract.Transforming growth factor-beta 1 induces apoptosis through Fas ligand-independent activation of the Fas death pathway in human gastric SNU-620 carcinoma cells.Role of membrane sphingomyelin and ceramide in platform formation for Fas-mediated apoptosisThree is better than one: pre-ligand receptor assembly in the regulation of TNF receptor signaling.High molecular weight complex analysis of Epstein-Barr virus Latent Membrane Protein 1 (LMP-1): structural insights into LMP-1's homo-oligomerization and lipid raft associationFAS system deregulation in T-cell lymphoblastic lymphomaCD95-mediated cell signaling in cancer: mutations and post-translational modulations.Targeting the Fas/FasL signaling pathway in cancer therapy.Importance of reverse signaling of the TNF superfamily in immune regulation.Targeting of the tumor necrosis factor receptor superfamily for cancer immunotherapy.Lipid rafts and raft-mediated supramolecular entities in the regulation of CD95 death receptor apoptotic signaling.Organization and dynamics of Fas transmembrane domain in raft membranes and modulation by ceramide.Signaling active CD95 receptor molecules trigger co-translocation of inactive CD95 molecules into lipid raftsMolecular ordering of the initial signaling events of CD95.A fifteen-amino-acid TVB peptide serves as a minimal soluble receptor for subgroup B avian leukosis and sarcoma viruses.Dominant negative effects of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 4 on TRAIL receptor 1 signaling by formation of heteromeric complexesDeath receptor 4 (DR4) efficiently kills breast cancer cells irrespective of their sensitivity to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL).CD95 Signaling Inhibits B Cell Receptor-Mediated Gammaherpesvirus Replication in Apoptosis-Resistant B Lymphoma Cells.Pre-assembly of the extracellular domains of CD40 is not necessary for rescue of mouse B cells from anti-immunoglobulin M-induced apoptosis.Ligand-independent signaling by overexpressed CD30 drives NF-kappaB activation in Hodgkin-Reed-Sternberg cells.CD95/Fas, Non-Apoptotic Signaling Pathways, and Kinases.Glutamine deprivation-mediated cell shrinkage induces ligand-independent CD95 receptor signaling and apoptosis.Potentiation of Fas-mediated apoptosis by an engineered glycosylphosphatidylinositol-linked Fas.Virus Infection and Death Receptor-Mediated Apoptosis.Retinoic acid regulates Fas-induced apoptosis in Jurkat T cells: reversal of mitogen-mediated repression of Fas DISC assembly.Nonapoptotic functions of Fas/CD95 in the immune response.Death Receptor 5 Activation Is Energetically Coupled to Opening of the Transmembrane Domain Dimer.Structural principles of tumor necrosis factor superfamily signaling.Sketching of CD95 Oligomers by In Silico Investigations.A novel role of microtubular cytoskeleton in the dynamics of caspase-dependent Fas/CD95 death receptor complexes during apoptosis.Oligomerization of soluble Fas antigen induces its cytotoxicity.
P2860
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P2860
Identification and characterization of a ligand-independent oligomerization domain in the extracellular region of the CD95 death receptor.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh
1999年學術文章
@zh-hant
name
Identification and characteriz ...... on of the CD95 death receptor.
@en
type
label
Identification and characteriz ...... on of the CD95 death receptor.
@en
prefLabel
Identification and characteriz ...... on of the CD95 death receptor.
@en
P2093
P2860
P356
P1476
Identification and characteriz ...... on of the CD95 death receptor.
@en
P2093
P2860
P304
38241-38250
P356
10.1074/JBC.274.53.38241
P407
P577
1999-12-01T00:00:00Z