Patient-derived xenografts recapitulate molecular features of human uveal melanomas.
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Uveal Melanoma Patient-Derived XenograftsUpcoming translational challenges for uveal melanomaPrognostic parameters in uveal melanoma and their association with BAP1 expression.Targeting Bcl-2/Bcl-XL induces antitumor activity in uveal melanoma patient-derived xenograftsTranscriptional dissection of pancreatic tumors engrafted in mice.Establishment of patient-derived tumor xenograft (PDTX) models using samples from CT-guided percutaneous biopsyEstablishment of an orthotopic patient-derived xenograft mouse model using uveal melanoma hepatic metastasisUpregulation of HLA Expression in Primary Uveal Melanoma by Infiltrating LeukocytesNanobodies against surface biomarkers enable the analysis of tumor genetic heterogeneity in uveal melanoma patient-derived xenografts.Validation of a preclinical model for assessment of drug efficacy in melanoma.Minimal contribution of ERK1/2-MAPK signalling towards the maintenance of oncogenic GNAQQ209P-driven uveal melanomas in zebrafishThe biology of uveal melanomaUveal Melanoma Cell Lines: Where do they come from? (An American Ophthalmological Society Thesis).Patient-derived tumor xenograft models for melanoma drug discovery.Establishment of novel cell lines recapitulating the genetic landscape of uveal melanoma and preclinical validation of mTOR as a therapeutic target.KRAS and PIK3CA mutation frequencies in patient-derived xenograft models of pancreatic and colorectal cancer are reflective of patient tumors and stable across passagesDual inhibition of protein kinase C and p53-MDM2 or PKC and mTORC1 are novel efficient therapeutic approaches for uveal melanoma.
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P2860
Patient-derived xenografts recapitulate molecular features of human uveal melanomas.
description
2013 nî lūn-bûn
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2013年の論文
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2013年学术文章
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2013年学术文章
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2013年学术文章
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2013年学术文章
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name
Patient-derived xenografts recapitulate molecular features of human uveal melanomas.
@en
type
label
Patient-derived xenografts recapitulate molecular features of human uveal melanomas.
@en
prefLabel
Patient-derived xenografts recapitulate molecular features of human uveal melanomas.
@en
P2093
P2860
P50
P1433
P1476
Patient-derived xenografts recapitulate molecular features of human uveal melanomas.
@en
P2093
André Nicolas
Audrey Rapinat
Bruno Tesson
Cécile Laurent
David Gentien
Didier Decaudin
Fariba Némati
J William Harbour
Jérôme Couturier
Laurence Desjardins
P2860
P304
P356
10.1016/J.MOLONC.2013.02.004
P50
P577
2013-02-26T00:00:00Z