Synergistic interaction between histone deacetylase and topoisomerase II inhibitors is mediated through topoisomerase IIbeta.
about
Anti-cancer drugs elicit re-expression of UDP-glucuronosyltransferases in melanoma cellsThe HDAC inhibitor valproate induces a bivalent status of the CD20 promoter in CLL patients suggesting distinct epigenetic regulation of CD20 expression in CLL in vivo.The histone deacetylase inhibitor valproic acid sensitizes diffuse large B-cell lymphoma cell lines to CHOP-induced cell death.Novel mechanism by which histone deacetylase inhibitors facilitate topoisomerase IIα degradation in hepatocellular carcinoma cellsPhase 1 study of valproic acid in pediatric patients with refractory solid or CNS tumors: a children's oncology group reportHistone deacetylase inhibition redistributes topoisomerase IIβ from heterochromatin to euchromatinRational therapeutic combinations with histone deacetylase inhibitors for the treatment of cancerBAD phosphorylation determines ovarian cancer chemosensitivity and patient survival.Phase I trial of vorinostat and doxorubicin in solid tumours: histone deacetylase 2 expression as a predictive marker.An overview of the visualisation and quantitation of low and high MW DNA adducts using the trapped in agarose DNA immunostaining (TARDIS) assay.The histone deacetylase inhibitor PXD101 increases the efficacy of irinotecan in in vitro and in vivo colon cancer models.Combination of HDAC and topoisomerase inhibitors in small cell lung cancer.The histone deacetylase inhibitor vorinostat selectively sensitizes fibrosarcoma cells to chemotherapy.Chromatin remodelling at the topoisomerase II-beta promoter is associated with enhanced sensitivity to etoposide in human neuroblastoma cell linesHistone deacetylase inhibitors induce FPGS mRNA expression and intracellular accumulation of long-chain methotrexate polyglutamates in childhood acute lymphoblastic leukemia: implications for combination therapy.Phase I/II trial of vorinostat with rituximab, cyclophosphamide, etoposide and prednisone as palliative treatment for elderly patients with relapsed or refractory diffuse large B-cell lymphoma not eligible for autologous stem cell transplantation.Pendant HDAC inhibitor SAHA derivatised polymer as a novel prodrug micellar carrier for anticancer drugs.Combination Therapy With Histone Deacetylase Inhibitors (HDACi) for the Treatment of Cancer: Achieving the Full Therapeutic Potential of HDACi.
P2860
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P2860
Synergistic interaction between histone deacetylase and topoisomerase II inhibitors is mediated through topoisomerase IIbeta.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
@yue
2005年學術文章
@zh
2005年學術文章
@zh-hant
name
Synergistic interaction betwee ...... through topoisomerase IIbeta.
@en
type
label
Synergistic interaction betwee ...... through topoisomerase IIbeta.
@en
prefLabel
Synergistic interaction betwee ...... through topoisomerase IIbeta.
@en
P2093
P1476
Synergistic interaction betwee ...... through topoisomerase IIbeta.
@en
P2093
Adil I Daud
Daniel M Sullivan
Douglas C Marchion
Elona Bicaku
Joel G Turner
Pamela N Munster
P304
P356
10.1158/1078-0432.CCR-05-1073
P407
P577
2005-12-01T00:00:00Z