about
Digitoxin and a synthetic monosaccharide analog inhibit cell viability in lung cancer cellsMonosaccharide digitoxin derivative sensitize human non-small cell lung cancer cells to anoikis through Mcl-1 proteasomal degradationCryptocaryol Structure-Activity Relationship Study of Cancer Cell Cytotoxicity and Ability to Stabilize PDCD4A novel use of gentamicin in the ROS-mediated sensitization of NCI-H460 lung cancer cells to various anticancer agentsDigitoxin and its synthetic analog MonoD have potent antiproliferative effects on lung cancer cells and potentiate the effects of hydroxyurea and paclitaxelA Direct Comparison of the Anticancer Activities of Digitoxin MeON-Neoglycosides and O-Glycosides: Oligosaccharide Chain Length-Dependent Induction of Caspase-9-Mediated ApoptosisImproving the affinity of SL0101 for RSK using structure-based design.Merremoside D: de novo synthesis of the purported structure, NMR analysis, and comparison of spectral data.Stereochemical survey of digitoxin monosaccharides: new anticancer analogues with enhanced apoptotic activity and growth inhibitory effect on human non-small cell lung cancer cell.Structure Activity Relationship Study of the Cleistriosides and Cleistetrosides for Antibacterial/Anticancer Activity.De novo synthesis of natural products via the asymmetric hydration of polyenes.Modulators of Na/K-ATPase: a patent review.De novo asymmetric synthesis of the pyranoses: from monosaccharides to oligosaccharides.Biosynthesis and Total Synthesis Studies on The Jadomycin Family of Natural Products.Nigericin decreases the viability of multidrug-resistant cancer cells and lung tumorspheres and potentiates the effects of cardiac glycosides.C3'/C4'-Stereochemical Effects of Digitoxigenin α-L-/α-D-Glycoside in Cancer Cytotoxicity.Digitoxin analogues with improved anticytomegalovirus activity.De novo asymmetric synthesis and biological evaluation of the trisaccharide portion of PI-080 and vineomycin B2.De Novo Asymmetric Syntheses of (+)-Goniothalamin, (+)-Goniothalamin oxide and 7,8-Bis-epi-Goniothalamin using Asymmetric Allylations.Synthesis of SL0101 carbasugar analogues: carbasugars via Pd-catalyzed cyclitolization and post-cyclitolization transformationsMetabolite induction of Caenorhabditis elegans dauer larvae arises via transport in the pharynx.De novo asymmetric synthesis of fridamycin E.De novo synthesis and biological evaluation of C6″-substituted C4″-amide analogues of SL0101.De novo asymmetric synthesis of D- and L-swainsonine.C5'-Alkyl Substitution Effects on Digitoxigenin α-l-Glycoside Cancer Cytotoxicity.De novo asymmetric synthesis of oligo-rhamno di- and tri-saccharides related to the anthrax tetrasaccharideDe novo formal synthesis of (-)-apicularen A via an iterative asymmetric hydration sequence.Synthesis of several cleistrioside and cleistetroside natural products via a divergent de novo asymmetric approach.Synthesis of aza-analogues of the glycosylated tyrosine portion of mannopeptimycin-E.De novo asymmetric syntheses of SL0101 and its analogues via a palladium-catalyzed glycosylation.Structure activity relationship study of Mezzettiasides natural products and their four new disaccharide analogues for anticancer/antibacterial activity.Total synthesis of tetrahydrolipstatin and stereoisomers via a highly regio- and diastereoselective carbonylation of epoxyhomoallylic alcohols.De Novo Asymmetric Syntheses of d-, l- and 8-epi-Swainsonine.Synthesis and Structure-Activity Relationship Study of 5a-Carbasugar Analogues of SL0101.Roles of the synergistic reductive O-methyltransferase GilM and of O-methyltransferase GilMT in the gilvocarcin biosynthetic pathway.A de novo approach to the synthesis of glycosylated methymycin analogues with structural and stereochemical diversityDe novo synthesis of 2-substituted syn-1,3-diols via an iterative asymmetric hydration strategy.De novo asymmetric synthesis of all-D-, all-L-, and D-/L-oligosaccharides using atom-less protecting groups.A stereoselective synthesis of digitoxin and digitoxigen mono- and bisdigitoxoside from digitoxigenin via a palladium-catalyzed glycosylation.De novo formal synthesis of (-)-virginiamycin M2 via the asymmetric hydration of dienoates.
P50
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P50
description
hulumtues
@sq
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
George A O'Doherty
@ast
George A O'Doherty
@en
George A O'Doherty
@es
George A O'Doherty
@nl
George A O'Doherty
@sl
type
label
George A O'Doherty
@ast
George A O'Doherty
@en
George A O'Doherty
@es
George A O'Doherty
@nl
George A O'Doherty
@sl
prefLabel
George A O'Doherty
@ast
George A O'Doherty
@en
George A O'Doherty
@es
George A O'Doherty
@nl
George A O'Doherty
@sl
P1053
G-3885-2012
P106
P21
P31
P3829
P496
0000-0002-1699-2249